Results 71 to 80 of about 3,783,966 (306)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Valuing Companies with a Fixed Book-Value Leverage Ratio [PDF]

open access: yesSSRN Electronic Journal, 2005
We develop valuation formulae for a company that maintains a fixed book-value leverage ratio and claim that it is more realistic than to assume, as Miles-Ezzell (1980), a fixed market-value leverage ratio. The value of tax shields depends only on the present value of the net increases of debt.
openaire   +1 more source

Reflections on Multiple Perspective Problem Framing [PDF]

open access: yes, 2011
The researchers have developed a system of value innovation modelling founded on the application of a multiple perspective problem framing theory (English 2008).
English, Stuart, Moor, Tim
core  

Nuclear Power: a Hedge against Uncertain Gas and Carbon Prices? [PDF]

open access: yes, 2006
High fossil fuel prices have rekindled interest in nuclear power. This paper identifies specific nuclear characteristics making it unattractive to merchant generators in liberalised electricity markets, and argues that non-fossil fuel technologies have ...
David M. Newbery   +4 more
core   +3 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Co-resistance Among Escherichia coli and Klebsiella pneumoniae Urine Isolates from Female Outpatients with Presumed UTI: A Retrospective US Cohort Study

open access: yesInfectious Diseases and Therapy
Introduction Urinary tract infections (UTIs) caused by antimicrobial-resistant Enterobacterales are a global health threat. There are limited surveillance data available to characterize the prevalence of antimicrobial resistance among outpatients in the ...
Keith S. Kaye   +7 more
doaj   +1 more source

Is it worth the hype? Influence of Artificial Intelligence efforts on key financial company metrics

open access: yesCopernican Journal of Finance & Accounting
Artificial Intelligence poses a consortium of multiple digital technologies able to perform tasks which were thought about that they can only be done by humans.
Daniel Maier
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

Communication, Company Mission, Organizational Values, and Company Performance

open access: yesProcedia - Social and Behavioral Sciences, 2018
Abstract Although research confirms that company mission and organizational values may influence the performance of individual employees as well as the company, it is evident that explicitly or implicitly codified statements of company mission and organizational values are simply not enough. Employees should feel the meaning of the mission and values,
Valerij Dermol, Nada Trunk Širca
openaire   +1 more source

THE ROLE OF BIODIVERSITY DISCLOSURE IN SUSTAINABILITY REPORT ON FIRM VALUE [PDF]

open access: yes, 2018
Companies in achieving their goals are likely to have an impact on the environment. Company operational activities directly affect the decline in the amount of biodiversity and indirectly contribute to climate change.
DESWITA, Shindy Sri, HARTO, Puji
core  

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