Results 241 to 250 of about 24,814,063 (309)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Correction: Insights into periodontal disease: comparative analysis of animal models. [PDF]

Front Dent Med
Barik B, Chawla S, Satapathy BS, Pattanik SK, Kumar JA, Al-Farraj S, Pattnaik G, Sillanpää M.   +7 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A Comparative Analysis of the Determinants of Male, Female, and Total Life Expectancy in United States and China. [PDF]

Am J Mens Health
Qiu C, Xie Y, Jin C, Liu T.
europepmc   +1 more source

A comparative analysis

Eugenio Vaccari, Laura N. Coordes, Yseult Marique, Geo Quinot   +3 more
openaire   +1 more source

Comparative Analysis of Diversification Rates in Clonal and Non-Clonal Flowering Plants. [PDF]

Ecol Lett
Kadyan S, Klimešová J, Dimitrov D, Wang Z, Smyčka J, Herben T.   +5 more
europepmc   +1 more source

Comparative Analysis of Physicochemical Composition and Antioxidant Properties of Three Edible Mushroom Varieties. [PDF]

Molecules
Bamidele OP.
europepmc   +1 more source

"Domestic animal models of human respiratory diseases" : 26th Annual Symposium of the Veterinary Comparative Respiratory Society, Oklahoma City, Oklahoma, Oct. 29 - Nov. 1, 2008

, 2008

core  

Comparative Analysis of Metabolic and Developmental Changes Across Reproductive Stages in Breeding Pigeons. [PDF]

J Poult Sci
Ziying L, Chenjiahui Z, Rongkang Z, Huilin L, Can L, Haopeng L, Guohua T, Wuhao C, Shuangyan M, Huimin C, Xingyue Q, Yantao L, Yanhua H, Wei W, Shuo Z, Yayan L, Jie P.   +16 more
europepmc   +1 more source