Results 81 to 90 of about 1,657,556 (272)

Comparative Effectiveness Research and CAM [PDF]

The Journal of Alternative and Complementary Medicine, 2010
Aphrase that one hears increasingly these days in biomedical circles is “comparative effectiveness research” (CER). No doubt, part of the reason is the fact that the current administration in the United States has promised a large wave of funding for CER.
openaire   +2 more sources

Mindfulness-based interventions for mental well-being among people with multiple sclerosis: a systematic review and meta-analysis of randomised controlled trials [PDF]

, 2019
Objective: Impairment of mental well-being (anxiety, depression, stress) is common among people with multiple sclerosis (PwMS). Treatment options are limited, particularly for anxiety.
Booth, Jo, Lawrence, Margaret, Mercer , Stewart W., Ramparsad, Nitish, Simpson, Robert, Simpson, Sharon   +5 more
core   +2 more sources

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

Regional Validation and Recalibration of Clinical Predictive Models for Patients With Acute Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundHeart failure clinical practice guidelines recommend applying validated clinical predictive models (CPMs) to support decision making. While CPMs are now widely available, the generalizability of heart failure CPMs is largely unknown.
Benjamin S. Wessler, Robin Ruthazer, James E. Udelson, Mihai Gheorghiade, Faiez Zannad, Aldo Maggioni, Marvin A. Konstam, David M. Kent   +7 more
doaj   +1 more source

Comparative effectiveness research: Using systematic reviews and meta-analyses to synthesize empirical evidence [PDF]

, 2011
The increased demand for evidence-based health care practices calls for comparative effectiveness research (CER), namely the generation and synthesis of research evidence to compare the benefits and harms of alternative methods of care.
Katapodi, Maria C., Northouse, Laurel L.
core   +1 more source

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi, Alice Pozza, Luc Mertens, Adam Paul Yan, Sarah Alexander   +4 more
wiley   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Prevalence of pain reports in pediatric primary care and association with demographics, body mass index, and exam findings: a cross-sectional study

BMC Pediatrics, 2018
Background Pediatric pain is associated to patient weight and demographics in specialized settings, but pain prevalence and its associated patient attributes in general pediatric outpatient care are unknown.
Randall W. Grout, Rachel Thompson-Fleming, Aaron E. Carroll, Stephen M. Downs   +3 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Impact of early surveillance on safety signal identification in the CathPCI DELTA study

BMJ Surgery, Interventions, & Health Technologies, 2020
Objectives The CathPCI Data Extraction and Longitudinal Trend Analysis study was designed to determine the feasibility of conducting prospective surveillance of a large national registry to perform comparative safety analyses of medical devices.
Joseph Drozda, Kathleen Hewitt, Danica Marinac-Dabic, Sharon-Lise Normand, Arjun Majithia, Michael E Matheny, Frederic S Resnic, Sourbha S Dani, Jessica K Paulus, Susan Robbins, Henry Ssemaganda, Angelo Ponirakis, Nilsa Loyo-Berrios, Issam Moussa   +13 more
doaj   +1 more source