Results 11 to 20 of about 174,992 (335)

Comparative genomic hybridization for the diagnosis of melanoma [PDF]

European Journal of Plastic Surgery, 2009
Despite advancements in protocols, a subset of melanocytic lesions continues to pose diagnostic challenges. This is particularly true in the pediatric population where certain congenital nevi mimic melanoma.
Ananth S. Murthy, Christopher Vanison, Neil Tanna   +2 more
core   +5 more sources

Genomic alterations detected by comparative genomic hybridization in ovarian endometriomas [PDF]

Brazilian Journal of Medical and Biological Research, 2010
Endometriosis is a complex and multifactorial disease. Chromosomal imbalance screening in endometriotic tissue can be used to detect hot-spot regions in the search for a possible genetic marker for endometriosis. The objective of the present study was to
L.C. Veiga-Castelli, J.C. Rosa e Silva, J. Meola, R.A. Ferriani, M. Yoshimoto, S.A. Santos, J.A. Squire, L. Martelli   +7 more
doaj   +6 more sources

Analysis of pilocytic astrocytoma by comparative genomic hybridization [PDF]

British Journal of Cancer, 2000
Very little is known about genetic abnormalities involved in the development of pilocytic astrocytoma, the most frequently occurring brain tumour of childhood. We have analysed 48 pilocytic astrocytoma specimens using comparative genomic hybridization.
Despina Sanoudou, Ola Tingby, M.A. Ferguson‐Smith, V. Peter Collins, Nicholas Coleman   +4 more
openalex   +3 more sources

Comparative Genomic Hybridization (CGH) in Genotoxicology [PDF]

, 2013
In the past two decades comparative genomic hybridization (CGH) and array CGH have become crucial and indispensable tools in clinical diagnostics. Initially developed for the genome-wide screening of chromosomal imbalances in tumor cells, CGH as well as array CGH have also been employed in genotoxicology and most recently in toxicogenomics.
Baumgartner, Adi, Hartleb, Veronika, Taylor, Jim   +2 more
openaire   +6 more sources

Comparative genomic hybridization

Annual Review of Genomics and Human Genetics, 2005
▪ Abstract  Altering DNA copy number is one of the many ways that gene expression and function may be modified. Some variations are found among normal individuals ( 14 , 35 , 103 ), others occur in the course of normal processes in some species ( 33 ), and still others participate in causing various disease states.
Daniel, Pinkel, Donna G, Albertson
openaire   +2 more sources

Comparative genomics reveals the hybrid origin of a macaque group [PDF]

Science Advances, 2023
Although species can arise through hybridization, compelling evidence for hybrid speciation has been reported only rarely in animals. Here, we present phylogenomic analyses on genomes from 12 macaque species and show that the fascicularis group originated from an ancient hybridization between the sinica
Zhang, Bao-Lin, Chen, Wu, Wang, Zefu, Pang, Wei, Luo, Meng-Ting, Wang, Sheng, Shao, Yong, He, Wen-Qiang, Deng, Yuan, Zhou, Long, Chen, Jiawei, Yang, Min-Min, Wu, Yajiang, Wang, Lu, Fernández-Bellon, Hugo, Molloy, Sandra, Meunier, Hélène, Wanert, Fanélie, Kuderna, Lukas, Marques-Bonet, Tomas, Roos, Christian, Qi, Xiao-Guang, Li, Ming, Liu, Zhijin, Schierup, Mikkel Heide, Cooper, David N., Liu, Jianquan, Zheng, Yong-Tang, Zhang, Guojie, Wu, Dong-Dong   +29 more
openaire   +8 more sources

Invasive melanoma in a 5-year-old Canadian patient: A case report

SAGE Open Medical Case Reports, 2019
Atypical Spitzoid lesions pose a distinct challenge in classification as they may comprise a mixture of both classic benign nevus and cutaneous melanoma characteristics.
Joanna Yuen, Fatmah AlZahrani, Garnet Horne, Karen Naert, Timothy McCalmont, Kathy Unger, Loretta Fiorillo   +6 more
doaj   +1 more source

Molecular cytogenetic characterization of mosaicism for a small supernumerary marker chromosome derived from chromosome 8 or r(8)(::p12→q13.1::) associated with phenotypic abnormalities

Taiwanese Journal of Obstetrics & Gynecology, 2016
Objective: We present molecular cytogenetic characterization of mosaicism for a small supernumerary marker chromosome (sSMC) derived from chromosome 8. Materials and Methods: A 35-year-old woman underwent amniocentesis at 16 weeks of gestation because of
Chih-Ping Chen, Shuan-Pei Lin, Yi-Hui Lin, Schu-Rern Chern, Peih-Shan Wu, Yen-Ni Chen, Shin-Wen Chen, Chien-Wen Yang, Wen-Lin Chen, Wayseen Wang   +9 more
doaj   +1 more source

Terminal microdeletion of chromosome 18 in a Malaysian boy characterized with few features of typical 18q- deletion syndrome: a case report

Journal of Medical Case Reports, 2023
Background The 18q- deletion syndrome is a rare congenital chromosomal disorder caused by a partial deletion of the long arm of chromosome 18. The diagnosis of a patient with this syndrome relies on the family medical history, physical examination ...
Azli Ismail, Fadly Ahid, Meow-Keong Thong, Zubaidah Zakaria   +3 more
doaj   +1 more source

Clinical applications of comparative genomic hybridization [PDF]

Genetics in Medicine, 1998
Comparative genomic hybridization (CGH) is a powerful DNA-based cytogenetic technique that allows the entire genome to be scanned for chromosomal imbalances without requiring the sample material to be mitotically active. During the past 2 years we received many requests from various medical centers around the country to use CGH to resolve the identity ...
Brynn Levy, Brynn Levy, Sara Kaffe, Sara Kaffe, Kurt Hirschhorn, Kurt Hirschhorn, T.M. Dunn, T.M. Dunn, Nataline B. Kardon, Nataline B. Kardon   +9 more
openaire   +3 more sources