Results 261 to 270 of about 265,128 (376)

Array comparative genomic hybridization analysis in patients with anophthalmia, microphthalmia, and coloboma

Genetics in Medicine, 2011
G. Raca, Craig A. Jackson, Laimutis Kučinskas, B. Warman, Joseph T C Shieh, A. Schneider, T. Bardakjian, L. Schimmenti   +7 more
semanticscholar   +1 more source

Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A‐Dependent Fatty Acid Oxidation

Advanced Science, EarlyView.
This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen, Jianqiang Yang, David O. Popoola, Fan Yang, Yajie Liu, Dongsheng Wang, Zhaohui S. Qin, Zhengjia Chen, Nabil F. Saba, Zhuo G. Chen, Yamin Li, Yong Teng   +11 more
wiley   +1 more source

Advantages of Array Comparative Genomic Hybridization Using Buccal Swab DNA for Detecting Pallister-Killian Syndrome. [PDF]

Ann Lab Med, 2019
Bertini V, Gana S, Orsini A, Bonuccelli A, Peroni D, Angelo V.   +5 more
europepmc   +1 more source

Genetic Alterations in Gastric Carcinomas and Adjacent Mucosa Detected by Comparative Genomic Hybridization (CGH) [PDF]

, 2001
Dong Wan Kim, Seok Jin Choi, Jee Young Lee, Kyu Jong Kim, Moo In Park, Seun Ja Park, Sun Hoe Koo, Ja Young Koo   +7 more
openalex   +1 more source

Genomic Variation Underpins Genetic Divergence and Differing Salt Resilience in Sesbania bispinosa

Advanced Science, EarlyView.
Sesbania, a leguminous halophyte, thrives in saline soils. Comparative genomics reveals key genomic variations—particularly chromosomal inversions—are identified as contributors to population differentiation and salt resilience. These findings advance the understanding of genomic variation driving evolution and phenotypic differentiation and offer ...
Gai Huang, Xiaofei Wang, Chengli Liu, Kaixuan He, Xiu‐Li Hou, Haofei Luo, Shuaibin Zhang, Changqing You, Yajun Jia, Fuqiang Wang, Xianwei Song, Guodao Liu, Xian Deng, Xiaofeng Cao   +13 more
wiley   +1 more source

Birth of a Healthy Infant after Preimplantation Confirmation of Euploidy by Comparative Genomic Hybridization [PDF]

, 2001
L. Wilton, Robert Williamson, John McBain, David Edgar, Lucille Voullaire   +4 more
openalex   +1 more source

Validation of microarray comparative genomic hybridization for comprehensive chromosome analysis of embryos.

Fertility and Sterility, 2011
C. Gutiérrez-Mateo, P. Colls, J. Sánchez-García, T. Escudero, R. Prates, K. Ketterson, D. Wells, S. Munné   +7 more
semanticscholar   +1 more source

A Blast‐Resistant NLR Gene Confers Drought Resistance by Competitively Interacting with an E3 Ligase to Protect Phenylalanine Ammonia‐Lyase in Rice

Advanced Science, EarlyView.
The NLR protein PibH8 interacts with phenylalanine ammonia‐lyase OsPAL1 and E3 ubiquitin ligase OsFBK16. Through competitive binding, PibH8 weakens the interaction between OsFBK16 and OsPAL1, thereby reducing the degradation of OsPAL1 by OsFBK16. The Hap1 allele of PibH8 exhibits a higher expression level than Hap2, thus accumulating more PibH8 protein,
Denghao Xiang, Haifu Tu, Yang Yuan, Yilong Yao, Wanwen Liao, Huaijun Wang, Yu Yan, Yao Wang, Yu Chen, Di Liu, Qingya Lv, Haidong He, Honghong Hu, Xuelei Lai, Meng Yuan, Haiyan Xiong, Faming Dong, Lizhong Xiong   +17 more
wiley   +1 more source

Array comparative genomic hybridization and its applications in cancer

Nature Genetics, 2005
D. Pinkel, D. Albertson
semanticscholar   +1 more source

Comparative Genomic Hybridization in Cancer Investigations

, 2003
Mario A. J. A. Hermsen, Paul J. van Diest, Marjan M. Weiss, Gerrit A. Meijer   +3 more
openaire   +3 more sources