Results 251 to 260 of about 88,145 (306)

Demystified....comparative genomic hybridization

Journal of clinical pathology, 1999
Weiss, M.M., Hermsen, M.A.J.A., Meijer, G.A., van Grieken, N.C.T., Baak, J.P.A., Kuipers, E.J., van Diest, P.J.   +6 more
openaire   +2 more sources

Comparative Genomic Hybridization Technique

, 2003
Screening for chromosomal changes in solid tumors was long hindered by methodological problems encountered in standard cytogenetic analysis. Comparative genomic hybridization (CGH), a technique that emerged in 1992 (1) has proved to be a powerful tool for molecular cytogenetic analysis of neoplasms.
W E, El-Rifai, S, Knuutila
openaire   +3 more sources

Comparative genomic hybridization in ganglioneuroblastomas

Cancer Genetics and Cytogenetics, 2002
The ganglioneuroblastoma are rare lesions with widespread neuronal differentiation that have been classified as intermediate stages between neuroblastoma and ganglioneuroma. To identify overall chromosome aberrations in ganglioneuroblastoma, we performed comparative genomic hybridization.
Toraman A.D., Keser, Lüleci G., Tunal N., Gelen T.   +4 more
openaire   +3 more sources

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Quantitative analysis of comparative genomic hybridization

Cytometry, 1995
AbstractComparative genomic hybridization (CGH) is a new molecular cytogenetic method for the detection of chromosomal imbalances. Following cohybridization of DNA prepared from a sample to be studied and control DNA to normal metaphase spreads, probes are detected via different fluorochromes.
Stanislas Du Manoir, Evelin Schrock, Martin Bentz   +2 more
exaly   +3 more sources

Detection of oncogene amplifications in medulloblastomas by comparative genomic hybridization and array-based comparative genomic hybridization

Journal of Neurosurgery: Pediatrics, 2004
Few studies have been conducted to investigate the genomic survey of oncogene amplification in medulloblastoma. Low frequency of N-myc, C-myc, and epidermal grow factor receptor (EGFR) gene amplification (< 10%) has been reported in medulloblastoma.
Carol Y K, Tong, Angela B Y, Hui, Xiao-Lu, Yin, Jesse C S, Pang, Xian-Lun, Zhu, Wai-Sang, Poon, Ho-Keung, Ng   +6 more
openaire   +3 more sources

Challenges in array comparative genomic hybridization for the analysis of cancer samples

Genetics in Medicine, 2007
PURPOSE: To address some of the challenges facing the incorporation of array comparative genomic hybridization technology as a clinical tool, including archived tumor tissue, tumor heterogeneity, DNA quality and quantity, and array comparative genomic ...
Norma J Nowak, Jeffrey Miecznikowski, David D Smith   +2 more
exaly   +2 more sources

Diagnostic utility of array‐based comparative genomic hybridization in a clinical setting [PDF]

American Journal of Medical Genetics, Part A, 2007
Array-based comparative genomic hybridization is a recently introduced technique for the detection of submicroscopic genomic imbalances (deletions or duplications) across the entire genome.
Hagit N Baris, Wen-Hann Tan, Virginia Kimonis   +2 more
exaly   +2 more sources

Comparative Genomic Hybridization

Current Protocols in Human Genetics, 1995
AbstractComparative Genomic Hybridization (CGH) is a powerful molecular cytogenetic technique that permits assessment of DNA copy number on a genome‐wide scale. Of note, this methodology uses tumor DNA as a probe for fluorescence in situ hybridization (FISH) to normal metaphase chromosomes and does not require dividing cells from the tumor specimen ...
S, DeVries, J W, Gray, D, Pinkel, F M, Waldman, D, Sudar   +4 more
openaire   +2 more sources