Results 21 to 30 of about 174,992 (335)

Comparative Genomic Hybridization

open access: yesArchives of Pathology & Laboratory Medicine, 2001
Comparative genomic hybridization (CGH) allows a genome-wide survey of the relative copy number of tumor DNA in a single hybridization. The tumor-cell DNA (Test DNA) is hybridized together with a sex-matched normal DNA (Reference DNA) onto normal metaphase spreads.
Tatiana Loukianova   +5 more
openaire   +6 more sources

Chromosome mapping of dragline silk genes in the genomes of widow spiders (araneae, theridiidae) [PDF]

open access: yes, 2010
With its incredible strength and toughness, spider dragline silk is widely lauded for its impressive material properties. Dragline silk is composed of two structural proteins, MaSp1 and MaSp2, which are encoded by members of the spidroin gene family ...
Ayoub, NA, Hayashi, CY, Zhao, Y
core   +7 more sources

1p36 deletion syndrome confirmed by fluorescence hybridization and array-comparative genomic hybridization analysis [PDF]

open access: yesKorean Journal of Pediatrics, 2016
Pediatric epilepsy can be caused by various conditions, including specific syndromes. 1p36 deletion syndrome is reported in 1 in 5,000–10,000 newborns, and its characteristic clinical features include developmental delay, mental retardation, hypotonia ...
Dong Soo Kang, Eunsim Shin, Jeesuk Yu
doaj   +1 more source

The complex hybrid origins of the root knot nematodes revealed through comparative genomics [PDF]

open access: yes, 2013
Meloidogyne root knot nematodes (RKN) can infect most of the world's agricultural crop species and are among the most important of all plant pathogens.
Abad   +76 more
core   +3 more sources

CGHScan: finding variable regions using high-density microarray comparative genomic hybridization data

open access: yesBMC Genomics, 2006
Background Comparative genomic hybridization can rapidly identify chromosomal regions that vary between organisms and tissues. This technique has been applied to detecting differences between normal and cancerous tissues in eukaryotes as well as genomic ...
Rajashekara Gireesh   +7 more
doaj   +1 more source

Tracking the evolutionary pathways among Brazilian Lebiasina species (Teleostei: Lebiasinidae): a chromosomal and genomic comparative investigation [PDF]

open access: yesNeotropical Ichthyology, 2022
Despite several difficulties in chromosomal analyses of small-sized fishes, the cytogenetics of the Lebiasinidae was largely improved in the last years, showing differential patterns in the chromosomal evolution inside the family. In this context, it has
Priscila Polaquini de Macedo Leite   +7 more
doaj   +1 more source

Molecular cytogenetic analysis of formalin-fixed, paraffin-embedded solid tumors by comparative genomic hybridization after universal DNA-amplification [PDF]

open access: yes, 1993
We present a technique which allows the detection and chromosomal localization of DNA sequence copy number changes in solid tumor genomes from frozen sections and paraffin embedded, formalin fixed specimens. Based on comparative genomic hybridization and
Cremer, Thomas   +7 more
core   +1 more source

Image analysis in comparative genomic hybridization [PDF]

open access: yesCytometry, 1995
AbstractComparative genomic hybridization (CGH) is a new technique by which genomic imbalances can be detected by combining in situ suppression hybridization of whole genomic DNA and image analysis. We have developed software for rapid, quantitative CGH image analysis by a modification and extension of the standard software used for routine karyotyping
Claes Lundsteen   +6 more
openaire   +3 more sources

Genomic variations define divergence of water/wildlife-associated Campylobacter jejuni niche specialists from common clonal complexes [PDF]

open access: yes, 2011
Although the major food-borne pathogen Campylobacter jejuni has been isolated from diverse animal, human and environmental sources, our knowledge of genomic diversity in C.
Ashelford, KE   +14 more
core   +2 more sources

CAISMOV24, a new human low-grade serous ovarian carcinoma cell line

open access: yesBMC Cancer, 2017
Background The spontaneous immortalization of primary malignant cells is frequently assigned to their genetic instability during in vitro culturing. In this study, the new epithelial ovarian cancer cell line CAISMOV24 was described and compared with its ...
Rodrigo Fernandes da Silva   +8 more
doaj   +1 more source

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