Results 21 to 30 of about 80,578 (289)

Caryoscope: An Open Source Java application for viewing microarray data in a genomic context

BMC Bioinformatics, 2004
Background Microarray-based comparative genome hybridization experiments generate data that can be mapped onto the genome. These data are interpreted more easily when represented graphically in a genomic context.
Ball Catherine A, Hernandez-Boussard Tina, Rees Christian A, Awad Ihab AB, Sherlock Gavin   +4 more
doaj   +1 more source

High Resolution Comparative Genomic Hybridization Detects 7–8 Megabasepair Deletion in PCR Amplified DNA1

Analytical Cellular Pathology, 2001
We investigated if any change in spatial resolution of comparative genomic hybridization analysis could be detected when using DNA amplified by degenerate oligonucleotide primed PCR (DOP‐PCR) as opposed to the use of unamplified DNA.
Jacob Larsen, Anne Marie Ottesen, Maria Kirchhoff, Claes Lundsteen, Jørgen K. Larsen   +4 more
doaj   +1 more source

Chromosomal imbalances detected in primary bone tumors by comparative genomic hybridization and interphase fluorescence in situ hybridization

Genetics and Molecular Biology, 2003
We applied a combination of comparative genomic hybridization (CGH) and fluorescence in situ hybridization (FISH), to characterize the genetic aberrations in three osteosarcomas (OS) and one Ewing's sarcoma. CGH identified recurrent chromosomal losses at
Marcelo Razera Baruffi, Edgard Edward Engel, Jeremy Andrew Squire, Luis Gonzaga Tone, Silvia Regina Rogatto   +4 more
doaj   +1 more source

Comparative genomic hybridization identifies virulence differences in Streptococcus suis. [PDF]

PLoS ONE, 2014
Streptococcus suis is an important zoonotic pathogen. However, identification of virulent S. suis strains is complicated because of the high diversity of the species. Here we evaluated the genetic difference among S.
Han Zheng, Ruiting Lan, Xiao Zheng, Zhigang Cui, Zhijie Liu, Xuemei Bai, Shaobo Ji, Marcelo Gottschalk, Jianguo Xu   +8 more
doaj   +1 more source

Genomic Profiling by Array Comparative Genomic Hybridization Reveals Novel DNA Copy Number Changes in Breast Phyllodes Tumours

Cellular Oncology, 2009
Breast phyllodes tumour (PT) is a rare fibroepithelial tumour. The genetic alterations contributing to its tumorigenesis are largely unknown. To identify genomic regions involved in pathogenesis and progression of PTs we obtained genome-wide copy number ...
Arno Kuijper, Antoine M. Snijders, Els M. J. J. Berns, Vibeke Kuenen-Boumeester, Elsken van der Wall, Donna G. Albertson, Paul J. van Diest   +6 more
doaj   +1 more source

CAISMOV24, a new human low-grade serous ovarian carcinoma cell line

BMC Cancer, 2017
Background The spontaneous immortalization of primary malignant cells is frequently assigned to their genetic instability during in vitro culturing. In this study, the new epithelial ovarian cancer cell line CAISMOV24 was described and compared with its ...
Rodrigo Fernandes da Silva, Daniela Maira Cardozo, Gisele Olinto Libanio Rodrigues, Caroline Natânia de Souza-Araújo, Natacha Azussa Migita, Liliana Aparecida Lucci de Angelo Andrade, Sophie Derchain, José Andrés Yunes, Fernando Guimarães   +8 more
doaj   +1 more source

Identification of genomic alterations in pancreatic cancer using array-based comparative genomic hybridization. [PDF]

PLoS ONE, 2014
BACKGROUND: Genomic aberration is a common feature of human cancers and also is one of the basic mechanisms that lead to overexpression of oncogenes and underexpression of tumor suppressor genes.
Jian-Wei Liang, Zhi-Zhou Shi, Tian-Yun Shen, Xu Che, Zheng Wang, Su-Sheng Shi, Xin Xu, Yan Cai, Ping Zhao, Cheng-Feng Wang, Zhi-Xiang Zhou, Ming-Rong Wang   +11 more
doaj   +1 more source

Genomic profiling of oral squamous cell carcinoma by array-based comparative genomic hybridization. [PDF]

PLoS ONE, 2013
We designed a study to investigate genetic relationships between primary tumors of oral squamous cell carcinoma (OSCC) and their lymph node metastases, and to identify genomic copy number aberrations (CNAs) related to lymph node metastasis.
Shunichi Yoshioka, Yoshiyuki Tsukamoto, Naoki Hijiya, Chisato Nakada, Tomohisa Uchida, Keiko Matsuura, Ichiro Takeuchi, Masao Seto, Kenji Kawano, Masatsugu Moriyama   +9 more
doaj   +1 more source

Array comparative genomic hybridization with cyanin cis-platinum-labeled DNAs

BioTechniques, 2004
Fluorescent cis-platinum compounds that react with the N7 atom of guanine are useful for labeling nucleic acids in fluorescence hybridization applications.
Anton K. Raap, Marja J.M. van der Burg, Jeroen Knijnenburg, Eric Meershoek, Carla Rosenberg, Joe W. Gray, Joop Wiegant, J. Graeme Hodgson, Hans J. Tanke   +8 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source