Results 211 to 220 of about 2,755,876 (359)

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Author Correction: Genomic analysis finds no evidence of canonical eukaryotic DNA processing complexes in a free-living protist

Nature Communications, 2021
Dayana E. Salas-Leiva, Eelco C. Tromer, Bruce A. Curtis, Jon Jerlström-Hultqvist, Martin Kolisko, Zhenzhen Yi, Joan S. Salas-Leiva, Lucie Gallot-Lavallée, Shelby K. Williams, Geert J. P. L. Kops, John M. Archibald, Alastair G. B. Simpson, Andrew J. Roger   +12 more
doaj   +1 more source

Mechanisms of Cefiderocol Resistance in Carbapenemase-Producing Enterobacterales: Insights from Comparative Genomics. [PDF]

Antibiotics (Basel)
Tristancho-Baró A, López-Calleja AI, Milagro A, Ariza M, Viñeta V, Fortuño B, López C, Latorre-Millán M, Clusa L, Badenas-Alzugaray D, Martínez R, Torres C, Rezusta A.   +12 more
europepmc   +1 more source

Comparative genomics of chalcone synthase and Myb genes in the grass family.

, 2000
Virginia M. Oberholzer, Mary L. Durbin, Michael T. Clegg   +2 more
openalex   +2 more sources

Genomic Exploration of the Hemiascomycetous Yeasts: 21. Comparative functional classification of genes [PDF]

, 2000
Claude Gaillardin, Guillemette Duchâteau-Nguyen, Fredj Tekaia, Bertrand Llorente, Serge Casarégola, Claire Toffano‐Nioche, Michel Aigle, François Artiguenave, Gaëlle Blandin, Monique Bolotin‐Fukuhara, Elisabeth Bon, Philippe Brottier, Jacky de Montigny, Bernard Dujon, Pascal Durrens, Andrée Lépingle, Alain Malpertuy, Cécile Neuvéglise, Odile Ozier-Kalogéropoulos, Serge Potier, William Saurin, Michel Termier, Micheline Wésolowski‐Louvel, Patrick Wincker, Jean‐Luc Souciet, Jean Weissenbach   +25 more
openalex   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Comparative genomics analysis of Bacillus altitudinis G03 provides insights into its biocontrol and probiotic traits. [PDF]

BMC Genomics
Chen D, Lin J, Yan Y, Pi J, Xu JF, Chen L.   +5 more
europepmc   +1 more source

Genomic exploration of the hemiascomycetous yeasts: 18. Comparative analysis of chromosome maps and synteny with Saccharomyces cerevisiae [PDF]

, 2000
Bertrand Llorente, Alain Malpertuy, Cécile Neuvéglise, Jacky de Montigny, M. Aigle, François Artiguenave, Gallien Blandin, Monique Bolotin‐Fukuhara, E. Bon, Philippe Brottier, Serge Casarégola, Pascal Durrens, C. Gaillardin, A. Lépingle, Odile Ozier-Kalogéropoulos, S. Potier, William Saurin   +16 more
openalex  

Astroblastoma: Clinicopathologic Features and Chromosomal Abnormalities Defined by Comparative Genomic Hybridization

, 2000
Daniel J. Brat, Yuichi Hirose, Kenneth J. Cohen, Burt G. Feuerstein, Peter C. Burger   +4 more
openalex   +2 more sources

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source