Results 231 to 240 of about 3,218,020 (355)

Comparative genome analysis and genome evolution

, 2002
This thesis described a collection of bioinformatic analyses on complete genome sequence data. We have studied the evolution of gene content and find that vertical inheritance dominates over horizontal gene trasnfer, even to the extent that we can use the gene content to make genome phylogenies.
openaire   +2 more sources

A chromosome-scale assembly and comparative genomics of the Yunnanopilia longistaminata. [PDF]

Sci Data
Zhou Y, Liu G, Wang L, Liu J, Liu Z, Li S, Wang D.   +6 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

GenomeDepot: data management system for microbial comparative genomics. [PDF]

Bioinform Adv
Kazakov A, Deutschbauer AM.
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Comparative Genomics and Phylogenomics of the Mustelinae Lineage (Mustelidae, Carnivora). [PDF]

Genome Biol Evol
Totikov AA, Tomarovsky AA, Perelman PL, Bulyonkova TM, Serdyukova NA, Yakupova AR, Mohr D, Foerster DW, Grau Jipoulou JH, Beklemisheva VR, Sidorov M, Miranda I, Farelo L, Abramov AV, Krasheninnikova K, Mukhacheva AS, Panov VV, Balanovska E, Cherkasov N, Zub K, Scott AF, Melo-Ferreira J, Okhlopkov IM, Zhuk A, Koepfli KP, Graphodatsky AS, Kliver S.   +26 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Ten quick tips for using the NIH Comparative Genomics Resource. [PDF]

PLoS Comput Biol
Tvedte ES, Arighi C, Carson MB, Rasmussen LV, Holmes K, Murphy TD.   +5 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Correction to 'Unveiling the Potential of Lentilactobacillus hilgardii in Malolactic Fermentation: Comparative Genomics and Fermentation Dynamics'. [PDF]

Microb Biotechnol
europepmc   +1 more source