Comparative genomics of the parasite Trichomonas vaginalis reveals genes involved in spillover from birds to humans. [PDF]
Sullivan SA+26 more
europepmc +1 more source
Comparative Genomics, Marker Density and Statistical Analysis of Chromosome Rearrangements [PDF]
Daniel J. Schoen
openalex +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee+9 more
wiley +1 more source
Comparative genomics reveals key adaptive mechanisms in pathogen host-niche specialization. [PDF]
Zhang M, Han L, Liao C, Su W, Jiang C.
europepmc +1 more source
Evaluation of the Reliability of Chromosomal Imbalances Detected by Combined Use of Universal DNA Amplification and Comparative Genomic Hybridization [PDF]
Tomohiko Harada+6 more
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Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan+4 more
wiley +1 more source
Comparative genomics of native plasmids from plant pathogenic Gammaproteobacteria. [PDF]
Urriza M+4 more
europepmc +1 more source
A strategy combining flow sorting and comparative genomic hybridization for studying genetic aberrations at different stages of colorectal tumorigenesis in ulcerative colitis [PDF]
O. P. F. Clausen+6 more
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Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Functional Genomics and Comparative Genomics Analysis in Plants. [PDF]
Lu Y, Zou Q.
europepmc +1 more source