Results 221 to 230 of about 449,093 (327)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Comparative genomics reveals diversity and taxonomic relationships among <i>Clostridioides difficile</i> phages. [PDF]

Microbiol Spectr
Rolin MH, Mondal SI, Karim D, Jewel NA, Khan T, Rahman M, Akter A.   +6 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Comparative genomics of endemic <i>Staphylococcus aureus</i> ST1 in New Zealand. [PDF]

mSphere
Voss EM, Cook GM, Couldrey C, Ferguson SA, Harland C, Karkaba A, McDougall S, Morales SE, Rolfe J, Ussher JE, White RT, Williams L, Williamson J.   +12 more
europepmc   +1 more source

Additional file 22: of Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus

, 2017
Ronald P. de Vries, Robert Riley, Ad Wiebenga, Guillermo Aguilar‐Osorio, Sotiris Amillis, Cristiane Uchima, Gregor Anderluh, Mojtaba Asadollahi, Marion Askin, Kerrie Barry, Evy Battaglia, Özgür Bayram, Tiziano Benocci, Susanna Braus-Stromeyer, Camila Caldana, David Cánovas, Gustavo Cerqueira, Fusheng Chen, Wanping Chen, Cindy Choi, Alicia Clum, Renato P. dos Santos, André Damásio, George Diallinas, Tamás Emri, Erzsébet Fekete, Michel Flipphi, Susanne Freyberg, Antonia Gallo, Christos Gournas, Rob Habgood, Matthieu Hainaut, María Harispe, Bernard Henrissat, Kristiina Hildén, Ryan Hope, Abeer Hossain, Eugenia Karabika, Levente Karaffa, Zsolt Karányi, Nada Kraševec, Alan Kuo, Harald Kusch, Kurt LaButti, Ellen Lagendijk, Alla Lapidus, Anthony Levasseur, Erika Lindquist, Anna Lipzen, Antonio Logrieco, Andrew MacCabe, Miia Mäkelä, Iran Malavazi, Petter Melin, Vera Meyer, Natalia Mielnichuk, Márton Miskei, Ákos Molnár, Giuseppina Mulè, Chew Yee Ngan, Margarita Orejas, Erzsébet Orosz, Jean Ouedraogo, Karin Overkamp, Hee-Soo Park, Giancarlo Perrone, Francois Piumi, Peter J. Punt, Arthur F. J. Ram, Ana Ramón, Stefan Rauscher, Éric Record, Diego Mauricio Riaño‐Pachón, Vincent Robert, Julian Röhrig, Roberto Ruller, Asaf Salamov, Nadhira Salih, Rob Samson, Erzsébet Sándor, Manuel Sanguinetti, Tabea Schütze, Kristina Sepčić, Ekaterina Shelest, Gavin Sherlock, Vicky Sophianopoulou, Fábio M. Squina, Hui Sun, Antonia Susca, Richard Todd, Adrian Tsang, Shiela E. Unkles, Nathalie van de Wiele, Diana van Rossen-Uffink, Juliana Oliveira, Tammi Vesth, Jaap Visser, Jae‐Hyuk Yu, Miaomiao Zhou, Mikael Rørdam Andersen   +99 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Complete mitochondrial genomes of the Prototheca genus: comparative genomics and evolutionary insights. [PDF]

BMC Genomics
Wibberg D, Bakuła Z, García-Cunchillos I, Gawor J, Gromadka R, Karnkowska A, Bielecki J, Jagielski T.   +7 more
europepmc   +1 more source

Chromosomal Regions in Prostatic Carcinomas Studied by Comparative Genomic Hybridization, Hierarchical Cluster Analysis and Self‐Organizing Feature Maps [PDF]

, 2002
Torsten Mattfeldt, H. Wolter, Danilo Trijic, Hans‐Werner Gottfried, Hans A. Kestler   +4 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Probing Viral Dark Matter: Comparative Genomics of Atypical Bacillus Phage YungSlug. [PDF]

Viruses
Johnson AA, Hale A, Sehnouni A, Gbadamosi Z, Boyd BM.   +4 more
europepmc   +1 more source