Results 311 to 320 of about 423,383 (346)
Some of the next articles are maybe not open access.
Comparative Genomic Hybridization
Current Protocols in Cell Biology, 2004AbstractComparative genomic hybridization (CGH) is a screening method based on fluorescence in situ hybridization (FISH). In contrast to conventional FISH, the metaphase target is derived from a normal peripheral blood lymphocyte culture. This target is hybridized to the test or tumor DNA, which is labeled/detected by one fluorochrome (i.e., green ...
Jane Bayani, Jeremy A. Squire
openaire +3 more sources
Comparative genomics: the bacterial pan-genome
Current Opinion in Microbiology, 2008Bacterial genome sequencing has become so easy and accessible that the genomes of multiple strains of more and more individual species have been and will be generated. These data sets provide for in depth analysis of intra-species diversity from various aspects.
Tettelin H, Riley D, Cattuto C, Medini D
openaire +4 more sources
Comparative mycobacterial genomics
Current Opinion in Microbiology, 1998Genomics is providing us with a mass of information about the biochemistry, physiology and pathogenesis of Mycobacterium tuberculosis and Mycobacterium leprae. Comparison of the two genome sequences is mutually enriching and indicates that the M. leprae genome appears to have undergone shrinkage and large-scale gene inactivation, which may account for ...
openaire +3 more sources
Comparative Genomics in Drosophila
2017Since the pioneering studies of Thomas Hunt Morgan and coworkers at the dawn of the twentieth century, Drosophila melanogaster and its sister species have tremendously contributed to unveil the rules underlying animal genetics, development, behavior, evolution, and human disease.
Martin Oti +2 more
openaire +3 more sources
Comparative Genomics for Prokaryotes
2017Bacteria and archaea, collectively known as prokaryotes, have in general genomes that are much smaller than those of eukaryotes. As a result, thousands of these genomes have been sequenced. In prokaryotes, gene architecture lacks the intron-exon structure of eukaryotic genes (with an occasional exception).
Alice R. Wattam +2 more
openaire +3 more sources
Comparative Genomic Hybridization
2003Numerical genetic changes can be most easily examined by simply preparing metaphase chromosomes and counting the number of chromosomes in the spread. Unfortunately, it is often impossible to obtain high-quality metaphase preparations from samples, especially solid tumors.
openaire +6 more sources
The Populus Genome and Comparative Genomics [PDF]
, 2009 Populus was the first tree genome, and one of the first plant genomes, to be sequenced. The sequencing project and subsequent annotation was a collaborative, international effort, with the bulk of the sequencing carried out by the US Department of Energy Joint Genome Institute.
Stephen P. DiFazio, Carl J. Douglas
openaire +1 more source
Genome Mapping in Plant Comparative Genomics
Trends in Plant Science, 2016Genome mapping produces fingerprints of DNA sequences to construct a physical map of the whole genome. It provides contiguous, long-range information that complements and, in some cases, replaces sequencing data. Recent advances in genome-mapping technology will better allow researchers to detect large (>1kbp) structural variations between plant ...
Joshua A. Udall +3 more
openaire +2 more sources
Genome screening by comparative genomic hybridization
Trends in Genetics, 1997Comparative genomic hybridization (CGH) provides a molecular cytogenetic approach for genome-wide scanning of differences in DNA sequence copy number. The technique is now attracting wide-spread interest, especially among cancer researchers. The rapidly expanding database of CGH publications already covers about 1500 tumors and is beginning to reveal ...
Olli-P. Kallioniemi +4 more
openaire +3 more sources
Comparative Genomics of the Dictyostelids
2013The complete genomes of Dictyostelium discoideum, Dictyostelium purpureum, Polysphondylium pallidum and Dictyostelium fasciculatum have been sequenced. The proteins predicted to be encoded by the genes in each species have been compared to each other as well as to the complete compilation of nonredundant proteins from bacteria, plants, fungi, and ...
openaire +3 more sources