Results 311 to 320 of about 3,218,020 (355)
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A phylogenetic approach to comparative genomics
Nature Reviews GeneticsAnna E Dewar +2 more
exaly +2 more sources
PLoS Biology, 2003 Comparing the genomes of two different species allow the exploration of a host of intriguing evolutionary and genetic ...
Ross C Hardison
exaly +7 more sources
Annual Review of Genomics and Human Genetics, 2004
▪ Abstract The genomes from three mammals (human, mouse, and rat), two worms, and several yeasts have been sequenced, and more genomes will be completed in the near future for comparison with those of the major model organisms. Scientists have used various methods to align and compare the sequenced genomes to address critical issues in genome ...
Webb, Miller +3 more
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▪ Abstract The genomes from three mammals (human, mouse, and rat), two worms, and several yeasts have been sequenced, and more genomes will be completed in the near future for comparison with those of the major model organisms. Scientists have used various methods to align and compare the sequenced genomes to address critical issues in genome ...
Webb, Miller +3 more
openaire +2 more sources
Comparative Apicomplexan genomics
Nature Reviews Microbiology, 2005 The power of comparative genomics has, until recently, been limited to model organisms and prokaryotes, mainly because of the cost and difficulty of sequencing eukaryotic genomes.
Arnab Pain +2 more
exaly +2 more sources
Comparative Genomic Hybridization
Current Protocols in Cell Biology, 2004AbstractComparative genomic hybridization (CGH) is a screening method based on fluorescence in situ hybridization (FISH). In contrast to conventional FISH, the metaphase target is derived from a normal peripheral blood lymphocyte culture. This target is hybridized to the test or tumor DNA, which is labeled/detected by one fluorochrome (i.e., green ...
Jane, Bayani, Jeremy A, Squire
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Comparative Genomic Hybridization
Current Protocols in Human Genetics, 1995AbstractComparative Genomic Hybridization (CGH) is a powerful molecular cytogenetic technique that permits assessment of DNA copy number on a genome‐wide scale. Of note, this methodology uses tumor DNA as a probe for fluorescence in situ hybridization (FISH) to normal metaphase chromosomes and does not require dividing cells from the tumor specimen ...
S, DeVries +4 more
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Comparative Genomics of Microsporidia
2022The microsporidia are a phylum of intracellular parasites that represent the eukaryotic cell in a state of extreme reduction, with genomes and metabolic capabilities embodying eukaryotic cells in arguably their most streamlined state. Over the past 20 years, microsporidian genomics has become a rapidly expanding field starting with sequencing of the ...
Williams, BAP, Williams, TA, Trew, J
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2017
Newly sequenced genomes are being added to the tree of life at an unprecedented fast pace. Increasingly, such new genomes are phylogenetically close to previously sequenced and annotated genomes. In other cases, whole clades of closely related species or strains ought to be annotated simultaneously.
Stefanie, König +2 more
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Newly sequenced genomes are being added to the tree of life at an unprecedented fast pace. Increasingly, such new genomes are phylogenetically close to previously sequenced and annotated genomes. In other cases, whole clades of closely related species or strains ought to be annotated simultaneously.
Stefanie, König +2 more
openaire +2 more sources
Comparative Genomic Hybridization
2003Numerical genetic changes can be most easily examined by simply preparing metaphase chromosomes and counting the number of chromosomes in the spread. Unfortunately, it is often impossible to obtain high-quality metaphase preparations from samples, especially solid tumors.
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Comparative mycobacterial genomics
Current Opinion in Microbiology, 1998Genomics is providing us with a mass of information about the biochemistry, physiology and pathogenesis of Mycobacterium tuberculosis and Mycobacterium leprae. Comparison of the two genome sequences is mutually enriching and indicates that the M. leprae genome appears to have undergone shrinkage and large-scale gene inactivation, which may account for ...
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