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Plasmodium comparative genomics [PDF]

Briefings in Functional Genomics, 2019
Malaria is a serious infectious disease caused by unicellular eukaryotic parasites of the genus Plasmodium. Today more than 200 species exist [1], and whole-genome sequence data is available for around 22 species [2]. At least five different Plasmodium species can infect humans, of which Plasmodium falciparum is the major cause of morbidity and ...
Ranford-Cartwright, Lisa, Gómez-Díaz, Elena   +1 more
openaire   +3 more sources

Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2′-O-Methyl Mixmer Antisense Oligonucleotide

Molecules, 2016
In this study, we synthesised a morpholino nucleoside-uridine (MNA-U) phosphoramidite and evaluated the potential of a MNA-modified antisense oligonucleotide (AO) sequences to induce exon 23 skipping in mdx mouse myotubes in vitro towards extending the ...
Suxiang Chen, Bao T. Le, Kamal Rahimizadeh, Khalil Shaikh, Narinder Mohal, Rakesh N. Veedu   +5 more
doaj   +1 more source

Evolution and comparative genomics of the most common Trichoderma species

BMC Genomics, 2019
The growing importance of the ubiquitous fungal genus Trichoderma (Hypocreales, Ascomycota) requires understanding of its biology and evolution. Many Trichoderma species are used as biofertilizers and biofungicides and T. reesei is the model organism for
C. Kubicek, A. Steindorff, Komal Chenthamara, G. Manganiello, B. Henrissat, Jian Zhang, F. Cai, Alexey G. Kopchinskiy, Eva M. Kubicek, A. Kuo, R. Baroncelli, S. Sarrocco, E. Noronha, G. Vannacci, Q. Shen, I. Grigoriev, Irina S Druzhinina   +16 more
semanticscholar   +1 more source

The Evolution of Comparative Phylogeography: Putting the Geography (and More) into Comparative Population Genomics

Genome Biology and Evolution, 2021
Comparative population genomics is an ascendant field using genomic comparisons between species to draw inferences about forces regulating genetic variation.
S. Edwards, V. Robin, N. Ferrand, C. Moritz   +3 more
semanticscholar   +1 more source

Eukfinder: a pipeline to retrieve microbial eukaryote genome sequences from metagenomic data

mBio
Whole-genome shotgun (WGS) metagenomic sequencing of microbial communities enables the discovery of the functions, physiologies, and evolutionary histories of prokaryotic and eukaryotic microbes.
Dandan Zhao, Dayana E. Salas-Leiva, Shelby K. Williams, Katherine A. Dunn, Jason D. Shao, Andrew J. Roger   +5 more
doaj   +1 more source

Integrating coalescent species delimitation with analysis of host specificity reveals extensive cryptic diversity despite minimal mitochondrial divergence in the malaria parasite genus Leucocytozoon

BMC Evolutionary Biology, 2018
Background Coalescent methods that use multi-locus sequence data are powerful tools for identifying putatively reproductively isolated lineages, though this approach has rarely been used for the study of microbial groups that are likely to harbor many ...
Spencer C. Galen, Renato Nunes, Paul R. Sweet, Susan L. Perkins   +3 more
doaj   +1 more source

Exogenous Melatonin Attenuates Post-Harvest Decay by Increasing Antioxidant Activity in Wax Apple (Syzygium samarangense)

Frontiers in Plant Science, 2020
Wax apple is one of the most popular tropical fruit but undergoes serious post-harvest decay during storage, transportation and marketing. Melatonin (MT) plays important roles in plant growth, development and stress responses.
Yao Chen, Yanjie Zhang, Ghazala Nawaz, Chenxu Zhao, Yuxia Li, Tingting Dong, Mingku Zhu, Ximeng Du, Lei Zhang, Zongyun Li, Tao Xu   +10 more
doaj   +1 more source

Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics

The ISME Journal, 2018
The vitamin B12 family of cofactors known as cobamides are essential for a variety of microbial metabolisms. We used comparative genomics of 11,000 bacterial species to analyze the extent and distribution of cobamide production and use across bacteria ...
Amanda N. Shelton, Erica C. Seth, Kenny C. Mok, Andrew W. Han, S. Jackson, David Haft, M. Taga   +6 more
semanticscholar   +1 more source

Comparative genomics of Arabidopsis and maize: prospects and limitations

, 2002
Brendel V, Kurtz S, Walbot V. Comparative genomics of Arabidopsis and maize: prospects and limitations. Genome Biology. 2002;3(3): reviews1005.1.The completed Arabidopsis genome seems to be of limited value as a model for maize genomics.
Walbot, Virginia, Brendel, Volker, Kurtz, Stefan   +2 more
core   +1 more source

Comparative genomics of the major parasitic worms

Nature Genetics, 2017
Parasitic nematodes (roundworms) and platyhelminths (flatworms) cause debilitating chronic infections of humans and animals, decimate crop production and are a major impediment to socioeconomic development.
International Helminth Genomes Consortium
semanticscholar   +1 more source