Results 41 to 50 of about 2,398,914 (265)

Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2′-O-Methyl Mixmer Antisense Oligonucleotide

Molecules, 2016
In this study, we synthesised a morpholino nucleoside-uridine (MNA-U) phosphoramidite and evaluated the potential of a MNA-modified antisense oligonucleotide (AO) sequences to induce exon 23 skipping in mdx mouse myotubes in vitro towards extending the ...
Suxiang Chen, Bao T. Le, Kamal Rahimizadeh, Khalil Shaikh, Narinder Mohal, Rakesh N. Veedu   +5 more
doaj   +1 more source

The importance of genome sequence quality to microbial comparative genomics [PDF]

, 2019
The quality of microbial genome sequences has been a concern ever since the emergence of genome sequencing. The quality of the genome assemblies is dependent on the sequencing technology used and the aims for which the sequence was generated.
Smits, Theo H.M.
core   +1 more source

Eukfinder: a pipeline to retrieve microbial eukaryote genome sequences from metagenomic data

mBio
Whole-genome shotgun (WGS) metagenomic sequencing of microbial communities enables the discovery of the functions, physiologies, and evolutionary histories of prokaryotic and eukaryotic microbes.
Dandan Zhao, Dayana E. Salas-Leiva, Shelby K. Williams, Katherine A. Dunn, Jason D. Shao, Andrew J. Roger   +5 more
doaj   +1 more source

Integrating coalescent species delimitation with analysis of host specificity reveals extensive cryptic diversity despite minimal mitochondrial divergence in the malaria parasite genus Leucocytozoon

BMC Evolutionary Biology, 2018
Background Coalescent methods that use multi-locus sequence data are powerful tools for identifying putatively reproductively isolated lineages, though this approach has rarely been used for the study of microbial groups that are likely to harbor many ...
Spencer C. Galen, Renato Nunes, Paul R. Sweet, Susan L. Perkins   +3 more
doaj   +1 more source

Exogenous Melatonin Attenuates Post-Harvest Decay by Increasing Antioxidant Activity in Wax Apple (Syzygium samarangense)

Frontiers in Plant Science, 2020
Wax apple is one of the most popular tropical fruit but undergoes serious post-harvest decay during storage, transportation and marketing. Melatonin (MT) plays important roles in plant growth, development and stress responses.
Yao Chen, Yanjie Zhang, Ghazala Nawaz, Chenxu Zhao, Yuxia Li, Tingting Dong, Mingku Zhu, Ximeng Du, Lei Zhang, Zongyun Li, Tao Xu   +10 more
doaj   +1 more source

EDGAR: a software framework for the comparative analysis of prokaryotic genomes [PDF]

, 2009
Blom J, Albaum S, Doppmeier D, et al. EDGAR: a software framework for the comparative analysis of prokaryotic genomes. BMC Bioinformatics. 2009;10(1): 154.Background:The introduction of next generation sequencing approaches has caused a rapid increase in
Blom, Jochen, Albaum, Stefan ; https://orcid.org/, Jochen Blom, Martha Zakrzewski, Goesmann, Alexander ; https://orcid.org/, Alfred Puhler, Pühler, Alfred ; https://orcid.org/, Zakrzewski, Martha, Doppmeier, Daniel, Vorhölter, Frank-Jörg, Stefan P Albaum, Daniel Doppmeier, Frank-Jorg Vorholter, Alexander Goesmann   +13 more
core   +1 more source

Extreme mitochondrial reduction in a novel group of free-living metamonads

Nature Communications
Metamonads are a diverse group of heterotrophic microbial eukaryotes adapted to living in hypoxic environments. All metamonads but one harbour metabolically altered ‘mitochondrion-related organelles’ (MROs) with reduced functions, however the degree of ...
Shelby K. Williams, Jon Jerlström Hultqvist, Yana Eglit, Dayana E. Salas-Leiva, Bruce Curtis, Russell J. S. Orr, Courtney W. Stairs, Tuğba N. Atalay, Naomi MacMillan, Alastair G. B. Simpson, Andrew J. Roger   +10 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Comparative genomics on gene and single nucleotide level [PDF]

, 2013
Blom J. Comparative genomics on gene and single nucleotide level.
Blom, Jochen
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source