Results 21 to 30 of about 173,818 (165)

Integrated Analysis of Metabolome and Transcriptome Reveals the Difference in Flavonoid Biosynthesis between the Red- and White-Sarcocarp Pomelo Fruits

Metabolites, 2022
Flavonoids are bioactive secondary metabolites that play multiple roles in plants. However, studies on the flavonoid accumulation of the pomelo fruit are rare.
Chenxu Zhao, Jiajia Wang, Yuxia Li, Lei Zhang, Ghazala Nawaz, Shaoyuan Wu, Tao Xu   +6 more
doaj   +1 more source

Dynamics of GATA1 binding and expression response in a GATA1-induced erythroid differentiation system

Genomics Data, 2015
During the maturation phase of mammalian erythroid differentiation, highly proliferative cells committed to the erythroid lineage undergo dramatic changes in morphology and function to produce circulating, enucleated erythrocytes.
Deepti Jain, Tejaswini Mishra, Belinda M. Giardine, Cheryl A. Keller, Christapher S. Morrissey, Susan Magargee, Christine M. Dorman, Maria Long, Mitchell J. Weiss, Ross C. Hardison   +9 more
doaj   +1 more source

Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology

Nature Communications, 2019
Being man’s best friend, dogs have been bred and selected for certain morphologic traits and breed-associated behaviours. Here, Plassais et al. analyse 722 canine whole genome sequences including modern breeds, wild canids and village dogs by GWAS and ...
Jocelyn Plassais, Jaemin Kim, Brian W. Davis, Danielle M. Karyadi, Andrew N. Hogan, Alex C. Harris, Brennan Decker, Heidi G. Parker, Elaine A. Ostrander   +8 more
doaj   +1 more source

Next-generation sequencing yields complete mitochondrial genome assembly of peaceful betta fish, Betta imbellis (Teleostei: Osphronemidae)

Mitochondrial DNA. Part B. Resources, 2020
The complete mitochondrial genome (mitogenome) of the peaceful betta (Betta imbellis) was obtained using next-generation sequencing. The sample of B. imbellis was collected from its native habitat in Southern Thailand.
Syed Farhan Ahmad, Nararat Laopichienpong, Worapong Singchat, Aorarat Suntronpong, Tavun Pongsanarm, Thitipong Panthum, Nattakan Ariyaraphong, Jakaphan Bulan, Tanawat Pansrikaew, Kornsuang Jangtarwan, Navapong Subpayakom, Sahabhop Dokkaew, Narongrit Muangmai, Prateep Duengkae, Kornsorn Srikulnath   +14 more
doaj   +1 more source

Reconstruction of proto-vertebrate, proto-cyclostome and proto-gnathostome genomes provides new insights into early vertebrate evolution

Nature Communications, 2021
Early vertebrate genomes were shaped by multiple whole-genome duplication (WGD) events of debated timings. Here the authors’ reconstruction of ancestral genomes using the probabilistic macrosynteny model supports a WGD shared by all vertebrates and a ...
Yoichiro Nakatani, Prashant Shingate, Vydianathan Ravi, Nisha E. Pillai, Aravind Prasad, Aoife McLysaght, Byrappa Venkatesh   +6 more
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Comparative genome assembly [PDF]

Briefings in Bioinformatics, 2004
One of the most complex and computationally intensive tasks of genome sequence analysis is genome assembly. Even today, few centres have the resources, in both software and hardware, to assemble a genome from the thousands or millions of individual sequences generated in a whole-genome shotgun sequencing project.
Mihai Pop, Adam M. Phillippy, Arthur L. Delcher, Steven Salzberg   +3 more
openaire   +3 more sources

The evolution of comparative genomics [PDF]

Molecular Genetics & Genomic Medicine, 2014
In this commentary I have only highlighted a few dimensions that comparative genomics has reached into. Looking at a PubMed search of publications with the exact combination and order of the words “comparative genomics” in the title or abstract identifies 3752 articles as of the date of this writing.
openaire   +2 more sources

Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2′-O-Methyl Mixmer Antisense Oligonucleotide

Molecules, 2016
In this study, we synthesised a morpholino nucleoside-uridine (MNA-U) phosphoramidite and evaluated the potential of a MNA-modified antisense oligonucleotide (AO) sequences to induce exon 23 skipping in mdx mouse myotubes in vitro towards extending the ...
Suxiang Chen, Bao T. Le, Kamal Rahimizadeh, Khalil Shaikh, Narinder Mohal, Rakesh N. Veedu   +5 more
doaj   +1 more source

Eukfinder: a pipeline to retrieve microbial eukaryote genome sequences from metagenomic data

mBio
Whole-genome shotgun (WGS) metagenomic sequencing of microbial communities enables the discovery of the functions, physiologies, and evolutionary histories of prokaryotic and eukaryotic microbes.
Dandan Zhao, Dayana E. Salas-Leiva, Shelby K. Williams, Katherine A. Dunn, Jason D. Shao, Andrew J. Roger   +5 more
doaj   +1 more source

Integrating coalescent species delimitation with analysis of host specificity reveals extensive cryptic diversity despite minimal mitochondrial divergence in the malaria parasite genus Leucocytozoon

BMC Evolutionary Biology, 2018
Background Coalescent methods that use multi-locus sequence data are powerful tools for identifying putatively reproductively isolated lineages, though this approach has rarely been used for the study of microbial groups that are likely to harbor many ...
Spencer C. Galen, Renato Nunes, Paul R. Sweet, Susan L. Perkins   +3 more
doaj   +1 more source