Results 31 to 40 of about 3,218,020 (355)

Comparative genomics in chicken and Pekin duck using FISH mapping and microarray analysis [PDF]

open access: yes, 2009
BACKGROUND: The availability of the complete chicken (Gallus gallus) genome sequence as well as a large number of chicken probes for fluorescent in-situ hybridization (FISH) and microarray resources facilitate comparative genomic studies between ...
Ioannou, D.   +30 more
core   +1 more source

Mitochondrial genome of bronze-winged jacana (Metopidius indicus, Latham 1790)

open access: yesMitochondrial DNA. Part B. Resources, 2021
We reported the mitochondrial genome (mitogenome) of bronze-winged jacana (Metopidius indicus, Latham ). The circular mitogenome was 17,208 base pairs (bp) in length, containing 13 protein-coding genes, two rRNAs, 22 tRNAs, and a non-coding control ...
Jitmat Thintip   +11 more
doaj   +1 more source

A comparative genomics multitool for scientific discovery and conservation

open access: yesNature, 2020
The Zoonomia Project is investigating the genomics of shared and specialized traits in eutherian mammals. Here we provide genome assemblies for 131 species, of which all but 9 are previously uncharacterized, and describe a whole-genome alignment of 240 ...
Diane P. Aitor Joel Jeremy Voichita D. Eva David Gill Ni Genereux Serres Armstrong Johnson Marinescu Murén   +48 more
semanticscholar   +1 more source

Comparative genomics - A perspective [PDF]

open access: yesBioinformation, 2007
The rapidly emerging field of comparative genomics has yielded dramatic results. Comparative genome analysis has become feasible with the availability of a number of completely sequenced genomes. Comparison of complete genomes between organisms allow for global views on genome evolution and the availability of many completely sequenced genomes ...
Selvarajan, Sivashankari   +1 more
openaire   +2 more sources

Novel Chemically-modified DNAzyme targeting Integrin alpha-4 RNA transcript as a potential molecule to reduce inflammation in multiple sclerosis

open access: yesScientific Reports, 2017
Integrin alpha-4 (ITGA4) is a validated therapeutic target for multiple sclerosis (MS) and Natalizumab, an antibody targeting ITGA4 is currently approved for treating MS. However, there are severe side effects related to this therapy.
Madhuri Chakravarthy   +3 more
doaj   +1 more source

RNA-Seq and iTRAQ reveal multiple pathways involved in storage root formation and development in sweet potato (Ipomoea batatas L.)

open access: yesBMC Plant Biology, 2019
Background Sweet potato (Ipomoea batatas L.) is the sixth most important food crop in the world. The formation and development of storage roots in sweet potato is a highly complicated and genetically programmed process. However, the underlying mechanisms
Tingting Dong   +7 more
doaj   +1 more source

Phytozome: a comparative platform for green plant genomics

open access: yesNucleic Acids Res., 2011
The number of sequenced plant genomes and associated genomic resources is growing rapidly with the advent of both an increased focus on plant genomics from funding agencies, and the application of inexpensive next generation sequencing.
D. Goodstein   +10 more
semanticscholar   +1 more source

Comparative genomic hybridization

open access: yesAnnual Review of Genomics and Human Genetics, 2005
▪ Abstract  Altering DNA copy number is one of the many ways that gene expression and function may be modified. Some variations are found among normal individuals ( 14 , 35 , 103 ), others occur in the course of normal processes in some species ( 33 ), and still others participate in causing various disease states.
Daniel, Pinkel, Donna G, Albertson
openaire   +2 more sources

Antisense Oligonucleotide-Mediated Terminal Intron Retention of the SMN2 Transcript

open access: yesMolecular Therapy: Nucleic Acids, 2018
The severe childhood disease spinal muscular atrophy (SMA) arises from the homozygous loss of the survival motor neuron 1 gene (SMN1). A homologous gene potentially encoding an identical protein, SMN2 can partially compensate for the loss of SMN1 ...
Loren L. Flynn   +4 more
doaj   +1 more source

The value of avian genomics to the conservation of wildlife [PDF]

open access: yes, 2009
Background: Genomic studies in non-domestic avian models, such as the California condor and white-throated sparrow, can lead to more comprehensive conservation plans and provide clues for understanding mechanisms affecting genetic variation, adaptation ...
Hickenbotham, Matthew T   +33 more
core   +1 more source

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