Results 11 to 20 of about 173,818 (165)

Comparative Genomics of the Eukaryotes [PDF]

open access: yesScience, 2000
A comparative analysis of the genomes of Drosophila melanogaster , Caenorhabditis elegans , and Saccharomyces cerevisiae —and the proteins they are predicted to encode—was undertaken in the context of cellular, developmental, and evolutionary processes.
Gerald M. Rubin   +55 more
openaire   +3 more sources

Comparative genomics of microsporidia [PDF]

open access: yesFolia Parasitologica, 2005
Microsporidia have been known for some time to possess among the smallest genomes of any eukaryote. There is now a completely sequenced microsporidian genome, as well as several other large-scale sequencing efforts, so the nature of these genomes is becoming apparent.
Patrick J, Keeling   +4 more
openaire   +2 more sources

Comparative genomics of Chlamydomonas

open access: yesThe Plant Cell, 2020
Abstract Despite its role as a reference organism in the plant sciences, the green alga Chlamydomonas reinhardtii entirely lacks genomic resources from closely related species. We present highly contiguous and well-annotated genome assemblies for three unicellular C.
Rory J Craig   +3 more
openaire   +3 more sources

Mitochondrial genome of bronze-winged jacana (Metopidius indicus, Latham 1790)

open access: yesMitochondrial DNA. Part B. Resources, 2021
We reported the mitochondrial genome (mitogenome) of bronze-winged jacana (Metopidius indicus, Latham ). The circular mitogenome was 17,208 base pairs (bp) in length, containing 13 protein-coding genes, two rRNAs, 22 tRNAs, and a non-coding control ...
Jitmat Thintip   +11 more
doaj   +1 more source

Comparative genomics of nematodes [PDF]

open access: yesTrends in Genetics, 2005
Recent transcriptome and genome projects have dramatically expanded the biological data available across the phylum Nematoda. Here we summarize analyses of these sequences, which have revealed multiple unexpected results. Despite a uniform body plan, nematodes are more diverse at the molecular level than was previously recognized, with many species ...
Mitreva, Makedonka   +3 more
openaire   +2 more sources

Novel Chemically-modified DNAzyme targeting Integrin alpha-4 RNA transcript as a potential molecule to reduce inflammation in multiple sclerosis

open access: yesScientific Reports, 2017
Integrin alpha-4 (ITGA4) is a validated therapeutic target for multiple sclerosis (MS) and Natalizumab, an antibody targeting ITGA4 is currently approved for treating MS. However, there are severe side effects related to this therapy.
Madhuri Chakravarthy   +3 more
doaj   +1 more source

RNA-Seq and iTRAQ reveal multiple pathways involved in storage root formation and development in sweet potato (Ipomoea batatas L.)

open access: yesBMC Plant Biology, 2019
Background Sweet potato (Ipomoea batatas L.) is the sixth most important food crop in the world. The formation and development of storage roots in sweet potato is a highly complicated and genetically programmed process. However, the underlying mechanisms
Tingting Dong   +7 more
doaj   +1 more source

Antisense Oligonucleotide-Mediated Terminal Intron Retention of the SMN2 Transcript

open access: yesMolecular Therapy: Nucleic Acids, 2018
The severe childhood disease spinal muscular atrophy (SMA) arises from the homozygous loss of the survival motor neuron 1 gene (SMN1). A homologous gene potentially encoding an identical protein, SMN2 can partially compensate for the loss of SMN1 ...
Loren L. Flynn   +4 more
doaj   +1 more source

Comparative genomic hybridization

open access: yesAnnual Review of Genomics and Human Genetics, 2005
▪ Abstract  Altering DNA copy number is one of the many ways that gene expression and function may be modified. Some variations are found among normal individuals ( 14 , 35 , 103 ), others occur in the course of normal processes in some species ( 33 ), and still others participate in causing various disease states.
Daniel, Pinkel, Donna G, Albertson
openaire   +2 more sources

Comparative genomics - A perspective [PDF]

open access: yesBioinformation, 2007
The rapidly emerging field of comparative genomics has yielded dramatic results. Comparative genome analysis has become feasible with the availability of a number of completely sequenced genomes. Comparison of complete genomes between organisms allow for global views on genome evolution and the availability of many completely sequenced genomes ...
Selvarajan, Sivashankari   +1 more
openaire   +2 more sources

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