Results 101 to 110 of about 1,297,255 (309)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Comparative of rules number by learning method.

open access: yes, 2019
Comparative of rules number by learning method.
Juan R. Castro (7349063)   +4 more
core   +1 more source

Unpacking Sources of Comparative Advantage: A Quantitative Approach [PDF]

open access: yes
This paper develops an approach for quantifying the importance of different sources of comparative advantage for country welfare. To explain patterns of specialization, I present a multi-country trade model that extends Eaton and Kortum (2002) to predict
Davin Chor
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Tendencias en educación y brecha regional. Indicadores del sistema educativo en Canarias (1990-2014)

open access: yesRevista Atlántida, 2020
En este artículo se tratará de mostrar, de forma descriptiva y comparativa, la evolución del sistema educativo canario (tomando como referencia desde los años 90 hasta la actualidad), con el objetivo de ofrecer una panorámica de la educación en Canarias ...
Josué Gutiérrez Barroso
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Developments in Comparative Public Law in South Africa

open access: yes
In South Africa, the study and practice of law involve comparing different legal systems due to the complex historical blend of Roman-Dutch, English, indigenous, and religious laws.
Geo Quinot
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Toward a Comparative Perspective on Corporate Governance and Labour Management [PDF]

open access: yes
While stakeholder models of corporate governance support long-term employment, recent reforms have promoted shareholder-oriented corporate governance worldwide. Will reform cause employment to converge on a market system? This paper presents a comparison
Gregory Jackson
core  

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