Results 121 to 130 of about 1,297,255 (309)

Presenting a Comparative Model of Hospital Management in Pandemic Conditions with Emphasis on the Pathology of Quaid Conditions 19

Journal of Preventive, Diagnostic and Treatment Strategies in Medicine
BACKGROUND: The COVID-19 pandemic exposed significant vulnerabilities in healthcare systems worldwide, emphasizing the need for robust hospital crisis management models tailored to infectious disease outbreaks.
Rahim Rouzbahani, Afsaneh Zamani Moghadam, Fereydoon Rahnamay Roodposhti   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

THE USE OF THE COMPARATIVE-COMPARATIVE METHOD IN TEACHING THE RUSSIAN LANGUAGE

, 2021
This article describes the method of using the comparative method in the process of teaching the Russian language. The comparative method provides for the students' awareness of the meaning of linguistic phenomena and the ways of their application in ...
Akbarova Dilorom Akhatovna, Tsagaraeva Olga Batyrbekovna   +1 more
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Revealing mammalian evolutionary relationships by comparative analysis of gene clusters

, 2012
Many software tools for comparative analysis of genomic sequence data have been released in recent decades. Despite this, it remains challenging to determine evolutionary relationships in gene clusters due to their complex histories involving ...
Riemer, C., Dickins, B., Riemer, C, Hsu, C-H, Kim, H.L., Green, ED, Hsu, C.-H., Miller, W., Zhang, Y, Hardison, R.C., Zhang, Y., Song, G, Kim, HL, Green, E.D., NISC Comparative Sequencing Program, Zhang, L., Zhang, L, Miller, W, Song, G., Hardison, RC, Dickins, B   +20 more
core   +1 more source

Faraway, so close. The comparative method and the potential of non-model animals in mitochondrial research. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2020
Milani L, Ghiselli F.
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

In support of the importance of development comparative method in sociology [PDF]

Zbornik Radova Filozofskog Fakulteta u Prištini, 2012
The importance of comparative methods in social research is now almost non-debatable. In contemporary sociological literature there are many papers that indicate the use of the sociological (and not only sociological) method.
Baščarević Ivan M.
doaj  

ICGEC: a comparative method for measuring epigenetic conservation of genes via the integrated signal from multiple histone modifications between cell types. [PDF]

BMC Genomics, 2020
Tang J, Wu Z, Tian Y, Yang R.
europepmc   +1 more source