Results 131 to 140 of about 49,054,835 (307)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Comparative Literature: Comparative Language? Vocalisations poétiques pour une pratique exophonique [PDF]
Butant contre les cadres normatifs, ce texte explore la possibilité de refigurer la littérature comparée par un décentrement de la pensée. It proposes to consider comparative language, not in an act of ranking one language over another, but in a gesture ...
Roussel, Flora
core
Texts and Images in a National, Comparative, and World Context [PDF]
, 2018 "To choose among national, comparative, and world literatures is a false choice. They are complementary. We cannot deny that we have nations today, partly created from internal colonization, and that colonization went hand in hand with external ...
Hart, Jonathan Locke
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
In support of the importance of development comparative method in sociology [PDF]
Zbornik Radova Filozofskog Fakulteta u Prištini, 2012 The importance of comparative methods in social research is now almost non-debatable. In contemporary sociological literature there are many papers that indicate the use of the sociological (and not only sociological) method.
Baščarević Ivan M.
doaj
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Faraway, so close. The comparative method and the potential of non-model animals in mitochondrial research. [PDF]
Philos Trans R Soc Lond B Biol Sci, 2020 Milani L, Ghiselli F.
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
ICGEC: a comparative method for measuring epigenetic conservation of genes via the integrated signal from multiple histone modifications between cell types. [PDF]
BMC Genomics, 2020 Tang J, Wu Z, Tian Y, Yang R.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source