Results 11 to 20 of about 3,258,123 (297)

Leveraging comparative phylogenetics for evolutionary medicine: applications to comparative oncology. [PDF]

Evol Med Public Health
Abstract Comparative phylogenetics provides a wealth of computational tools to understand evolutionary processes and their outcomes. Advances in these methodologies have occurred in parallel with a surge in cross-species genomic and phenotypic data.
Compton Mellon WJ, Sterner B, Ågren JA, Vincze O, Marx M, Kapsetaki S, Huang PH, Yavari B, McCollum HW, Natterson-Horowitz B, Human H, Baciu C, Richker H, Mallo D, Maley CC, Harmon L, Compton ZT.   +16 more
europepmc   +7 more sources

Comparative oncology: overcoming human cancer through companion animal studies. [PDF]

Exp Mol Med, 2023
Comparative oncology is a field of study that has been recently adopted for studying cancer and developing cancer therapies. Companion animals such as dogs can be used to evaluate novel biomarkers or anticancer targets before clinical translation.
Oh JH, Cho JY.
europepmc   +2 more sources

Divergent understandings in comparative oncology. [PDF]

Proc Natl Acad Sci U S A
Compton ZT, Boddy AM, Abegglen LM, Chávez D, Schiffman JD, Tollis M, Maley CC.   +6 more
europepmc   +3 more sources

Advancing cancer research via comparative oncology. [PDF]

Nat Rev Cancer
In the ongoing battle against cancer, the natural world provides promising inspiration for designing novel therapeutic strategies. The field of comparative oncology offers a valuable source of such inspiration. By combining evolutionary biology, ecology,
Vincze O, Spada B, Bilder D, Cagan A, DeGregori J, Gorbunova V, Maley CC, Schiffman JD, Seluanov A, Giraudeau M, Pradeu T.   +10 more
europepmc   +2 more sources

Insights from veterinary models for advancing oncolytic virotherapy through comparative oncology. [PDF]

Front Mol Biosci
Cancer is a complex disease affecting both humans and animals. Comparative immuno-oncology explores immune responses across species to develop effective cancer therapies.
Alkayyal AA.
europepmc   +2 more sources

Comparative Oncology: New Insights into an Ancient Disease. [PDF]

iScience, 2020
Cancer has deep evolutionary roots and is an important source of selective pressure in organismal evolution. Yet, we find a great deal of variation in cancer vulnerabilities across the tree of life.
Boddy AM, Harrison TM, Abegglen LM.
europepmc   +2 more sources

Integrating Radiation Oncology Into Undergraduate Medical Education [PDF]

, 2021
Cancer is one of the most important public health problems. However, medical education has not advanced at the same rate when it comes to cancer education.
Holmes, Jordan A., Olivier, Kenneth R., Arbab, Mona, Fields, Emma C., Kahn, Jenna M., Zellars, Richard C., Haywood, Antwione M., Corbin, Kimberly S., Kenneth R. Olivier, MD, Jenna M. Kahn, MD, Mona Arbab, Emma C. Fields, MD, Jenna M. Kahn, Richard C. Zellars, Jordan A. Holmes, Jordan A. Holmes, MD, MPH, Mona Arbab, MD, Antwione M. Haywood, Kimberly S. Corbin, MD, Kenneth R. Olivier, Emma C. Fields, Antwione M. Haywood, PhD, Kimberly S. Corbin, Richard C. Zellars, MD   +23 more
core   +1 more source

Comparative Oncology Today [PDF]

Veterinary Clinics of North America: Small Animal Practice, 2007
The value of comparative oncology has been increasingly recognized in the field of cancer research, including the identification of cancer-associated genes; the study of environmental risk factors, tumor biology, and progression; and, perhaps most importantly, the evaluation of novel cancer therapeutics. The fruits of this effort are expected to be the
Melissa C, Paoloni, Chand, Khanna
openaire   +2 more sources

Comparative Oncology of Companion Animals. [PDF]

Vet Sci
Cancer constitutes a significant clinical challenge in veterinary medicine, with a high prevalence among companion animals [...]
Faustino-Rocha AI, Oliveira PA, Gil da Costa RM.   +2 more
europepmc   +2 more sources

Improving Osteosarcoma Treatment: Comparative Oncology in Action. [PDF]

Life (Basel), 2022
Osteosarcoma (OSA) is the most common pediatric malignant bone tumor. Although surgery together with neoadjuvant/adjuvant chemotherapy has improved survival for localized OSA, most patients develop recurrent/metastatic disease with a dismally poor outcome. Therapeutic options have not improved for these OSA patients in recent decades.
Tarone L, Mareschi K, Tirtei E, Giacobino D, Camerino M, Buracco P, Morello E, Cavallo F, Riccardo F.   +8 more
europepmc   +4 more sources