Results 191 to 200 of about 5,352,427 (356)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Particulate trace metal chemistry in the open ocean and the Western Mediterranean : a comparative study

, 1980
Patrick Buat‐Ménard, M. Arnold, D N Baron, H. Benard, R. Chesselet   +4 more
openalex   +1 more source

Atherosclerosis: A Comparative Study [PDF]

BMJ, 1962
R, FINLAYSON, C, SYMONS, R N, FIENNES
openaire   +2 more sources

A Comparison of Postoperative Complications and Clinical Outcomes in Postless Versus Post-Assisted Hip Arthroscopy: A Systematic Review and Meta-analysis of Nonrandomized Comparative Studies. [PDF]

Orthop J Sports Med
Ajrawat P, Nikolopoulos M, Dwyer T, Hoit G, Whelan DB, Pathak A, Chahal J.   +6 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Comparative Study [PDF]

, 2020
openaire   +1 more source

Canine and feline mesenchymal stem cells: an integrative review of direct comparative studies by species and tissue source. [PDF]

J Vet Sci
Kim HS, Shin TH.
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Comparative Study of the Role of Trans-Boundary Rivers in Relations of Countries: The Case of Nile and Euphrates

, 2014
Seulaiman Hussen
openalex   +1 more source

Conventionally Fractionated Radiotherapy (CFRT) Versus Stereotactic Body Radiotherapy (SBRT) for Locally Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis of Comparative Studies. [PDF]

Cancers (Basel)
Montesi G, Miszczyk M, Niespolo RM, Capezzali G, Cellini F, D'Abbiero N, Fiore M, Genovesi D, La Macchia M, Lupattelli M, Mantello G, Matrone F, Nicosia L, Simoni N, Franco P, De Felice F.   +15 more
europepmc   +1 more source