Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Letter to the Editor: insights into "A comparative analysis of tip-bendable suction ureteral access sheath versus traditional sheath in retrograde intrarenal stone surgery: a systematic review and meta-analysis of comparative studies". [PDF]
Lin MS, Feng WJ, Liu HM.
europepmc +1 more source
No Evidence of Superior Graft Remodeling and Maturation When Adding a Lateral Extra-articular Procedure to Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis of Comparative Studies. [PDF]
D'Ambrosi R +6 more
europepmc +1 more source
Novel 5-Aryl-[1,2,4]triazoloquinazoline Fluorophores: Synthesis, Comparative Studies of the Optical Properties and ICT-Based Sensing Application. [PDF]
Kopotilova AE +6 more
europepmc +1 more source
Does Adding LEAP to ACL Reconstruction Reduce Graft Failure? A Systematic Review and Meta-Analysis of Comparative Studies with Minimum Two-Year Follow-Up. [PDF]
Giusti S +4 more
europepmc +1 more source
Clinical outcomes and complications in Latarjet versus free bone block procedures for anterior shoulder instability: a meta-analysis of comparative studies. [PDF]
Sulkowski A +4 more
europepmc +1 more source
Use of serotonergic antidepressants and perioperative complications in patients undergoing lower limb arthroplasty: Systematic review and meta-analysis of comparative studies. [PDF]
Grammatikopoulos D +5 more
europepmc +1 more source
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