Results 211 to 220 of about 266,111 (303)

Impact of digital supportive supervision (DiSS) on the extent of maternal and child healthcare service utilisation in India: a sequential mixed-methods quasi-experimental study. [PDF]

BMJ Open
Sharda S, Singh P, Trakroo A, Agrawal PK, Goyal A, Agarwal A, Chawla M, Joshi A, Singh S, Singh R, Kshtriya P, D'Aquino L, Kumar S, Prinja S.   +13 more
europepmc   +1 more source

Paternal use of metformin and risk of major congenital malformations: A meta‐analysis of 4 studies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Metformin is the first‐line drug for the treatment of Type 2 diabetes. In 2022, a Danish registry‐based study reported a 40% increased risk of major congenital malformations following paternal exposure during spermatogenesis. This raised widespread concern about the use of metformin in males of reproductive age.
Per Damkier, Marleen M. H. J. van Gelder, Krista F. Huybrechts, Lin‐Chieh Meng, Sonia Hernandez‐Diaz, Jan Nielsen, Bente M. Nørgård, Hedvig Nordeng   +7 more
wiley   +1 more source

Assessing Overall Survival Benefits in Advanced Cancers: The Role of External Comparator Cohort Studies with Real-World Data. [PDF]

Clin Pharmacol Ther
Pignatti F, El-Galaly TC, Kaiser M, Porkka K, Doeswijk R, Mol P, Rivera DR, Lerro CC, Rohr UP, Verpillat P, Valachis A, Trapani D, Di Maio M, Latino N, Cordoba R, Cherny N, Koopman M, Martins-Branco D, Pentheroudakis G, Postmus D.   +19 more
europepmc   +1 more source

Beyond standardisation, subjects and syllabi: How primary schools organise for arts richness in an era of curriculum reform

British Educational Research Journal, EarlyView.
Abstract As England embarks on its first comprehensive curriculum review in fifteen years, this paper offers critical insights from schools that sustained arts‐rich provision despite a policy landscape hostile to creative subjects. Drawing on data from the Researching Arts‐rich Primary Schools (RAPS) project—a mixed‐methods study of 76 arts‐rich ...
Pat Thomson, Christine Hall
wiley   +1 more source

First-Line Serplulimab versus Other Anti-PD-1/PD-L1 Antibodies Plus Chemotherapy for Esophageal Squamous Cell Carcinoma: A Systematic Review with Benefit-Risk Assessment via Matching-Adjusted Indirect Comparison. [PDF]

Biologics
Zhu Y, Qi X, Ni S, Qiu W, Chen M.
europepmc   +1 more source

Mimic, target, and adapt: Cell membrane‐coated nanoplatforms for precision and immune‐guided cancer treatment

BMEMat, EarlyView.
This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam, Xiaojun Cai, Malik Ihsan Ullah Khan, Robert Musiol, Quazi T. H. Shubhra   +4 more
wiley   +1 more source

Active Comparator New User Cohort Studies and Matching. [PDF]

JAMA Intern Med
Stürmer T, Wang T.
europepmc   +1 more source

The impacts of biological invasions

Biological Reviews, EarlyView.
ABSTRACT The Anthropocene is characterised by a continuous human‐mediated reshuffling of the distributions of species globally. Both intentional and unintentional introductions have resulted in numerous species being translocated beyond their native ranges, often leading to their establishment and subsequent spread – a process referred to as biological
Phillip J. Haubrock, Teun Everts, Neil Angelo S. Abreo, Jamie Bojko, Victor Deklerck, James W. E. Dickey, Ana Clara S. Franco, Emili García‐Berthou, Stelios Katsanevakis, Natalia I. Kirichenko, Stefano Mammola, Martin A. Nuñez, Ben Parker, Riccardo Scalera, Ismael Soto, Diederik Strubbe, Ali Serhan Tarkan, Lorenzo Vilizzi, Tim Adriaens, Paride Balzani, Dagmara Błońska, Elizabeta Briski, Rein Brys, Amy L. Burgess, James E. Byers, Carlos Cano‐Barbacil, Giuseppe Castaldelli, Jaimie T.A. Dick, Victoria Dominguez Almela, Romina D. Dimarco, Margarita Florencio, Antonín Kouba, Melina Kourantidou, Irmak Kurtul, Irene Martín‐Forés, Olivier Morissette, Julian D. Olden, Bruno E. Soares, Jakub Truszkowski, Hugo Verreycken, Marc Kenis, Ronaldo Sousa, J. Robert Britton   +42 more
wiley   +1 more source

Consensus for the most suitable trial design to assess therapy for rare vascular malformations: a Delphi study. [PDF]

Sci Rep
Allemang-Trivalle A, Giraudeau B, Maruani A.   +2 more
europepmc   +1 more source

Procedural Outcome of Modern Percutaneous Coronary Intervention in Proximal Chronic Total Occlusions

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Long‐term outcome in patients with chronic total occlusions (CTO) depends on the target vessel and proximity of the lesion. Aims To investigate of the target vessel was associated with procedural efficacy and safety in patients with proximal CTO lesions.
Emil N. Holck, Guiseppe Vadalá, Mohamed Ayoub, Sevket Gorgulu, Alexandre Avran, Gerald S. Werner, Kambis Mashayekhi, Nihat Kalay, Omer Goktekin, Jaroslaw Wojcik, Myron Zaczkiewicz, Roberto Garbo, Juergen Arenz, Jörg Dalibor, Bas Schölzel, Nicolas Boudou, Michael Behnes, Pierfrancesco Agostoni, Carlo Di Mario, Roberto Diletti, Juan Luis Guitiérrez‐Chico, Evald H. Christiansen   +21 more
wiley   +1 more source