Results 111 to 120 of about 12,729 (243)

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

open access: yesBritish Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller   +3 more
wiley   +1 more source

An Open-Source AMS Circuit Optimization Framework Based on Reinforcement Learning—From Specifications to Layouts

open access: yesIEEE Access
This paper presents a fully open-sourced AMS integrated circuit optimization framework based on reinforcement learning (RL). Specifically, given a certain circuit topology and target specifications, this framework optimizes the circuit in both schematic ...
Zonghao Li, Anthony Chan Carusone
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Incretin and Glucagon Signalling in MASLD and MASH: Integrating Metabolic Pathways With Disease Progression

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) arises from dysregulated interactions between nutrient delivery, adipose tissue lipid handling and liver lipid metabolism, which collectively coalesce to drive inflammatory signalling leading to metabolic dysfunction‐associated steatohepatitis (MASH) and fibrosis. Recent clinical
Evangelia E. Tsakiridis   +1 more
wiley   +1 more source

Past Carbon Emissions and Future Targets for the Olympic Games

open access: yesThe Geographical Journal, EarlyView.
Short Abstract The global visibility and political weight of the Olympic Games can inspire climate change action. Yet, at the same time, the Olympics are also significant carbon emitters. To date, however, there is a lack of a systematic assessment of past carbon emissions and extrapolation of future targets considering international agreements.
David Gogishvili, Martin Müller
wiley   +1 more source

A 2.1 GS/s 2-Channel Pipeline-SAR ADC With Speed-Enhanced Bootstrap Switch and Low-Latency SAR Logic

open access: yesIEEE Access
This paper introduces a 12-bit 2-channel interleaved Pipelined Successive Approximation Register (Pipelined-SAR) Analog-to-Digital Converter (ADC) capable of operating at 2.1 GS/s.
Tao Fu   +3 more
doaj   +1 more source

Dual task performance in adults with type 2 diabetes mellitus: A systematic review with meta‐analysis

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Background Daily activities require the simultaneous execution of cognitive and motor tasks. Type 2 diabetes mellitus (T2DM) is associated with functional impairments that may compromise dual‐task performance, leading to increased dual‐task interference.
Cristián Barros‐Osorio   +5 more
wiley   +1 more source

Three phase power factor controller [PDF]

open access: yes, 1984
A power control circuit for a three phase induction motor is described. Power factors for the three phases are summed to provide a control signal, and this control signal is particularly filtered and then employed to control the duty cycle of each phase ...
Nola, F. J.
core   +1 more source

Haploid Mutation Mapping Identifies a Homoeologous Non‐Reciprocal Translocation Linked to Reduced Fibre and Enhanced Protein in Brassica napus

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT A key challenge for the genetic improvement of canola (Brassica napus), one of the world's most important oilseeds, is the limited natural variation for commercially important traits. The creation of new variation is hindered by the lack of functional knowledge about genes controlling these traits.
Morgan W. Kirzinger   +30 more
wiley   +1 more source

A Multiproject Chip Approach to the Teaching of Analog MOS LSI and VLSI [PDF]

open access: yes, 1981
Multiproject chip implementation has been used in teaching analog MOS circuit design. After having worked with computer simulation and layout aids in homework problems, students designed novel circuits including several high performance op amps, an A/D ...
Antoniadis, Dimitri A.   +1 more
core  

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