Results 141 to 150 of about 426,729 (287)

Neuropsychiatric Outcomes Associated With GLP‐1 Receptor Agonist Use in Medicare Beneficiaries With Type 2 Diabetes: Variation by Treatment Pattern and Obesity Status

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Glucagon‐like peptide‐1 (GLP‐1) receptors are expressed in brain regions governing mood, reward and stress, yet the neuropsychiatric effects of GLP‐1 receptor agonist (GLP‐1 RA) therapy remain poorly characterized. We estimated associations between GLP‐1 RA use and neuropsychiatric disorders and variation by obesity status and treatment ...
Seo Hyon Baik, Fitsum Baye, Haotian Xian, Kin Wah Fung, Clement J. McDonald   +4 more
wiley   +1 more source

Novel targets in headache: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This narrative review summarizes novel applications for the use of calcitonin gene‐related peptide (CGRP)‐targeted therapies that go beyond migraine, the latest updates with respect to targeting pituitary adenylate cyclase‐activating peptide (PACAP) as therapeutic in migraine, as well as exploring other more recently ...
Adriana Della Pietra, Peter J. Goadsby, Carolina Oldoni, Stephen Silberstein, Fred Cohen, Simon Akerman   +5 more
wiley   +1 more source

The Role of Innate Lymphoid Cells in Autoimmune, Allergic and Infectious Diseases: A Systematic Review

Immunology, EarlyView.
This systematic review establishes disease‐specific dysregulations of human innate lymphoid cells (ILCs), demonstrating that an ILC1/ILC3 imbalance compromises mucosal barriers in inflammatory bowel disease, while activated ILC2s drive allergic airway inflammation.
Luan F. Lückmann, Henrique R. Dal‐Pizzol, Louise M. Lückmann, Davi E. Salini, Bruna C. Hasckel, Mikaeli Minati, Bruno Kluwe‐Schiavon, Tatiana Barichello   +7 more
wiley   +1 more source

Design Lab-Based Learning of Analog Front-End Circuits: A Sigma-Delta Modulator Lab

This paper details a Lab exercise that combines electrical and behavioral models to design ∑ΔMs. This Lab is suitable for students following an undergraduate course dealing with the design of analog-to-digital converters.
Leñero Bardallo, Juan Antonio, Méndez Romero, Roberto José, Rodríguez Vázquez, Ángel Benito, Gómez Merchán, Rubén   +3 more
core   +1 more source

A holistic approach to type 1 diabetes: From advances in science and technology to equity in diabetes care

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Over the past century, the discovery of insulin transformed type 1 diabetes from a fatal disease into a manageable chronic condition, and the subsequent recognition of its autoimmune basis laid the foundation for screening and intervention before clinical onset.
Noriko Kodani
wiley   +1 more source

Influence of GLP‐1‐Based Pharmacotherapies on Eating Behavior, Appetite, and Energy Intake in Adults With Overweight or Obesity: A Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
ABSTRACT Introduction Although GLP‐1‐based pharmacotherapies achieve clinically significant weight loss, their influence on eating behavior is unknown. Methods This systematic review examined the effects of GLP‐1‐based pharmacotherapies on eating behavior, appetite, and energy intake in adults (≥ 18 years) with overweight or obesity (BMI ≥ 25 kg/m2 ...
Clarissa Dakin, Jordan D. Beaumont, Beverley O′Hara   +2 more
wiley   +1 more source

Transdiagnostic patterns of electroencephalography (EEG)‐derived aperiodic activity across schizophrenia‐spectrum, bipolar, and depressive disorders: A systematic review

Psychiatry and Clinical Neurosciences, EarlyView.
Aperiodic electroencephalographic activity is proposed as a scalable marker of cortical population dynamics relevant to excitation–inhibition balance. However, it remains unclear whether aperiodic parameters represent disorder‐specific abnormalities or context‐sensitive indices of clinically relevant brain states.
Gia Han Le, Sabrina Wong, Sara Di Luch, Diana K. Orsini, Shreya Vasudeva, Sri Mahavir Agarwal, Cristian‐Daniel Llach, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

Lower Bounds for (Non-Monotone) Comparator Circuits.

Electron. Colloquium Comput. Complex., 2019
Comparator circuits are a natural circuit model for studying the concept of bounded fan-out computations, which intuitively corresponds to whether or not a computational model can make "copies" of intermediate computational steps. Comparator circuits are believed to be weaker than general Boolean circuits, but they can simulate Branching Programs and ...
Gál, Anna, Robere, Robert
openaire   +4 more sources

A low‐cost handheld device for monitoring cutaneous photosensitivity

Photochemistry and Photobiology, EarlyView.
The cutaneous photosensitivity detection (CPD) device is a handheld contact‐based measurement device using 405 nm excitation and red fluorescence detection for monitoring skin phototoxicity risk after photodynamic therapy (PDT) procedures involving systemic aminolaevulinic acid (ALA) induced protoporphyrin IX (PpIX) photosensitization.
Md Asaduzzaman Rasel, Ryan Beland, Shakir Khan, Tayyaba Hasan, Jonathan P. Celli   +4 more
wiley   +1 more source

64-bit high efficiency binary comparator in quantum-dot cellular automata

, 2016
Quantum-dot Cellular Automata (QCA) are proposed models of quantum computation, which are articulated in analogy to Von Neumann's conventional models of cellular automata.
Patalay, Dinkar
core