Results 101 to 110 of about 17,626,989 (327)
Neural Regeneration Research, 2015 OBJECTIVE: China is the only country where nerve growth factor is approved for large-scale use as a clinical medicine. More than 10 years ago, in 2003, nerve growth factor injection was listed as a national drug.
Meng Zhao +3 more
doaj +1 more source
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
A Neural Model of How The Brain Represents and Compares Numbers [PDF]
, 1999 Many psychophysical experiments have shown that the representation of numbers and numerical quantities in humans and animals is related to number magnitude.
Grossberg, Stephen, Repin, Dmitry
core +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Excess Molar Volume of Binary Systems Containing Mesitylene [PDF]
Kemija u Industriji, 2013 This paper presents a review of density measurements for binary systems containing 1,3,5-trimethylbenzene (mesitylene) with a variety of organic compounds at atmospheric pressure.
Morávková, L., Sedláková, Z.
doaj
Comparison between two accreditation criteria: A report on the differences between the IFOAM Accreditation Criteria and ISO 65 (EN 45011) [PDF]
, 2003 The paper describes the results of a comparison between two accreditation criteria: the IFOAM Accreditation Criteria and ISO 65 (EN 45011. The comparison does not provide an assessment of each norm, and the format of the comparison makes it difficult ...
Huber, Beate
core
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Reconstructed grounded theory: beyond comparison? [PDF]
, 2010 This paper examines the modifications made to constructed grounded theory for application within an ethnographic study of group work processes in a virtual learning environment.
Bradley, S. A.
core
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source