Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis
Advanced Biology, EarlyView.Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard +7 more
wiley +1 more source
Spatiotemporal Control Over Protein Release from Artificial Cells via a Light‐Activatable Protease
Advanced Biology, EarlyView.Stimulus‐responsive protein release is essential for intercellular communication. Mimicking this functionality in artificial cells is promising to study the working principles of cellular signaling. Herein, an engineered light‐activatable protease is implemented in a coacervate‐based artificial cell platform to establish user‐defined spatiotemporal ...
Arjan Hazegh Nikroo +4 more
wiley +1 more source
Comparison Principles for the Finsler Infinity Laplacian with Applications to Minimal Lipschitz Extensions [PDF]
arXivThis paper proves comparison principles for elliptic PDE involving the Finsler infinity Laplacian, a second-order differential operator with discontinuities in the gradient variable arising in $L^{\infty}$-variational problems and tug-of-war games. The core of the paper consists in proving generalized cone comparison principles.
arxiv
Advanced Biology, EarlyView.Coacervation driven by liquid‐liquid phase separation (LLPS) of biopolymers has garnered increasing attention in biology since this leads to the formation of membraneless organelles capable of performing essential yet largely unknown functions. This review highlights recent advances in coacervates (artificial condensates) composed of low‐molecular ...
Sayuri L. Higashi, Masato Ikeda
wiley +1 more source
Problems of Comparison in Social Sciences: Context vs. General Principle
, 2004 Nobuo Kanomata
openalex +2 more sources
Comparison of Massage Based on the Tensegrity Principle and Classic Massage in Treating Chronic Shoulder Pain [PDF]
, 2014 Graham Scarr
openalex +1 more source
Advanced Biology, EarlyView.The successful in situ polymerization of microtubules in giant polymer‐lipid hybrid vesicles is illustrated. The microtubules formed in the giant hybrid vesicles exhibit different morphologies including lumenal network formation and membrane association. Abstract Creating artificial cells with a dynamic cytoskeleton, akin to those in living cells, is a
Paula De Dios Andres +4 more
wiley +1 more source
A comparison principle for nonlocal coupled systems of fully nonlinear parabolic equations
, 2006 Rong-Nian Wang, Ti‐Jun Xiao, Jin Liang
openalex +1 more source
Comparison of Wind Energy Generation Using the Maximum Entropy Principle and the Weibull Distribution Function [PDF]
, 2016 Muhammad Shoaib +5 more
openalex +1 more source
Toward Design Principles for Biomolecular Condensates for Metabolic Pathways
Advanced Biology, EarlyView.Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André +3 more
wiley +1 more source