Results 121 to 130 of about 587,634 (306)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Nonuniqueness of solutions of initial-value problems for parabolic p-Laplacian
Electronic Journal of Differential Equations, 2015 We construct a positive solution to a quasilinear parabolic problem in a bounded spatial domain with the p-Laplacian and a nonsmooth reaction function. We obtain nonuniqueness for zero initial data.
Jiri Benedikt +4 more
doaj
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Comparison principle for positive time-delay systems: An extension and its application
, 2021 Comparison principle for positive time-delay systems: An extension and its ...
LQ Thuan (15822959) +3 more
core
Comparison principle for parabolic equations in the Heisenberg group
, 2005 We define two notions of viscosity solutions to parabolic equations in the Heisenberg group, depending on whether the test functions concern only the past or both the past and the future.
Bieske, Thomas
core +1 more source
Blowup and existence of global solutions to nonlinear parabolic equations with degenerate diffusion
Electronic Journal of Differential Equations, 2013 In this article, we consider the degenerate parabolic equation $$ u_t-\hbox{div}(|\nabla u|^{p-2}\nabla u) =\lambda u^m+\mu|\nabla u|^q $$ on a smoothly bounded domain $\Omega\subseteq\mathbb{R}^N\; (N\geq2)$, with homogeneous Dirichlet boundary ...
Zhengce Zhang, Yan Li
doaj
Comparison Principle for Weakly Coupled Cooperative Parabolic Systems with Delays
MathematicsIn this article, the validity of the comparison principle (CP) for weakly coupled quasi-linear cooperative systems with delays is proven. This is a powerful tool for studying the qualitative properties of the solutions. The CP is crucial in the proofs of
Georgi Boyadzhiev
doaj +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Global stability of stage-structured single species model on with Beverton–Holt birth function
Applied Mathematics in Science and EngineeringOur article discusses a Cauchy problem of a single species model with stage structure and Beverton–Holt birth function. The global stability of the Cauchy problem is completely surveyed by using the global stability of the corresponding elliptic system ...
Hongtao Zhang, Jingfu Zhao
doaj +1 more source
On the comparison principle in the calculus of variations
Arkiv för Matematik, 1983 On etudie des integrales variationnelles de la forme I(u,D)=∫ D F(x,⊇u(x))dx,DCG.
openaire +3 more sources