Results 101 to 110 of about 2,857,638 (285)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

p-harmonious functions with drift on graphs via games

open access: yesElectronic Journal of Differential Equations, 2011
In a connected finite graph $E$ with set of vertices $mathfrak{X}$, choose a nonempty subset, not equal to the whole set, $Ysubset mathfrak{X}$, and call it the boundary $Y=partialmathfrak{X}$.
Alexander P. Svirido
doaj  

A Weak Comparison Principle for Reaction-Diffusion Systems

open access: yesJournal of Function Spaces and Applications, 2012
We prove a weak comparison principle for a reaction-diffusion system without uniqueness of solutions. We apply the abstract results to the Lotka-Volterra system with diffusion, a generalized logistic equation, and to a model of fractional-order chemical ...
José Valero
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Existence and uniqueness for a dislocation model with short-range interactions and varying stress field

open access: yesElectronic Journal of Differential Equations, 2015
In this article, we consider a coupled singular parabolic system, describing the dynamics of dislocation densities in a bounded domain. The model takes into consideration the short-range interactions between dislocations, which causes the singularity ...
Hassan Ibrahim
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Nonuniqueness of solutions of initial-value problems for parabolic p-Laplacian

open access: yesElectronic Journal of Differential Equations, 2015
We construct a positive solution to a quasilinear parabolic problem in a bounded spatial domain with the p-Laplacian and a nonsmooth reaction function. We obtain nonuniqueness for zero initial data.
Jiri Benedikt   +4 more
doaj  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Blowup and existence of global solutions to nonlinear parabolic equations with degenerate diffusion

open access: yesElectronic Journal of Differential Equations, 2013
In this article, we consider the degenerate parabolic equation $$ u_t-\hbox{div}(|\nabla u|^{p-2}\nabla u) =\lambda u^m+\mu|\nabla u|^q $$ on a smoothly bounded domain $\Omega\subseteq\mathbb{R}^N\; (N\geq2)$, with homogeneous Dirichlet boundary ...
Zhengce Zhang, Yan Li
doaj  

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