Results 81 to 90 of about 2,857,638 (285)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A Note on the Relation of Weighting and Matching Estimators [PDF]
This paper compares the inverse-probability-of-selection-weighting estimation principle with the matching principle and derives conditions for weighting and matching to identify the same and the true distribution, respectively.
Michael Lechner
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Comparison Principles for the p-Laplacian Operator
Journal of Mathematical Sciences, 2014 In this paper the author proves new comparison principles for the \(p\)-Laplace operator, both in bounded and in unbounded domains. In bounded domains he applies an approach already developed in the literature for the case where \(1 < p\leq 2\), and extends it to the case \(p > 2\), using measure theory.
openaire +3 more sources
On maximal inequalities via comparison principle [PDF]
Journal of Inequalities and Applications, 2015 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
, 2016 We extend the generalised comparison principle for the Monge-Amp\`ere equation due to Rauch & Taylor (Rocky Mountain J. Math. 7, 1977) to nonconvex domains. From the generalised comparison principle we deduce bounds (from above and below) on solutions of
Ozanski, Wojciech
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Existence and regularity of weak solutions for singular elliptic problems
Electronic Journal of Differential Equations, 2015 In this article we study the semilinear singular elliptic problem $$\displaylines{ -\Delta u = \frac{p(x)}{u^{\alpha}}\quad \text{in } \Omega \cr u = 0\quad \text{on } \partial\Omega,\quad u>0 \text{ in } \Omega, }$$ where $\Omega$ is a regular ...
Brahim Bougherara +2 more
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