Results 81 to 90 of about 587,634 (306)
Comparison of Bayesian-Utilitarian and Maximin Principle Approaches
Human and Ecological Risk Assessment: An International Journal, 2005 The Precautionary Principle implies the adoption of a set of rules aimed at avoiding possible future harm associated with suspected, but not ascertained, risk factors. Several philosophical, economical and societal questions are implied by precaution-based public health decision making.
Pietro Comba +2 more
openaire +3 more sources
Model Comparison and the Principle of Parsimony [PDF]
, 2015 According to the principle of parsimony, model selection methods should value both descriptive accuracy and simplicity. Here we focus primarily on Bayes factors and minimum description length, explaining how these procedures strike a balance between goodness-of-fit and parsimony.
Joachim Vandekerckhove +2 more
openaire +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A singular ODE related to quasilinear elliptic equations
Electronic Journal of Differential Equations, 2000 We consider a quasilinear elliptic problem with the natural growth in the gradient. Existence, non-existence, uniqueness, and qualitative properties of positive solutions are obtained. We consider both weak and strong solutions.
Luka Korkut +2 more
doaj
ComputationMost solutions of fractional differential equations (FDEs) that model real-world phenomena in various fields of science, industry, and engineering are complex and cannot be solved analytically.
Khalid Hattaf
doaj +1 more source
The Pareto principle of optimal inequality [PDF]
inequality aversion, Pareto principle, uncertainty, time ...
BOMMIER, Antoine, ZUBER, Stéphane
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
A Lemma for a Strong Comparison Principle of Nonlinear Parabolic Equations [PDF]
, 2022 In this note, we prove a lemma for a strong comparison principle of nonlinear parabolic equations. We shall prove a function which is a viscosity subsolution minus a viscosity supersolution of the equation becomes a viscosity subsolution of a parabolic ...
カワイ, サトシ +7 more
core
Parabolic Biased Infinity Laplacian Equation Related to the Biased Tug-of-War
Advanced Nonlinear Studies, 2019 In this paper, we study the parabolic inhomogeneous β-biased infinity Laplacian equation arising from the β-biased tug-of ...
Liu Fang, Jiang Feida
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source