Results 131 to 140 of about 5,620,148 (306)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Decay estimates and extinction properties of parabolic equations with classical and fractional time derivatives

Electronic Journal of Differential Equations
In this article, we study the decay estimates and extinction properties of weak solutions to some parabolic equations with classical and fractional time derivatives.
Fanmeng Meng, Xian-Feng Zhou
doaj  

Blowup and existence of global solutions to nonlinear parabolic equations with degenerate diffusion

Electronic Journal of Differential Equations, 2013
In this article, we consider the degenerate parabolic equation $$ u_t-\hbox{div}(|\nabla u|^{p-2}\nabla u) =\lambda u^m+\mu|\nabla u|^q $$ on a smoothly bounded domain $\Omega\subseteq\mathbb{R}^N\; (N\geq2)$, with homogeneous Dirichlet boundary ...
Zhengce Zhang, Yan Li
doaj  

Comparison Principle for Weakly Coupled Cooperative Parabolic Systems with Delays

Mathematics
In this article, the validity of the comparison principle (CP) for weakly coupled quasi-linear cooperative systems with delays is proven. This is a powerful tool for studying the qualitative properties of the solutions. The CP is crucial in the proofs of
Georgi Boyadzhiev
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Global stability of stage-structured single species model on with Beverton–Holt birth function

Applied Mathematics in Science and Engineering
Our article discusses a Cauchy problem of a single species model with stage structure and Beverton–Holt birth function. The global stability of the Cauchy problem is completely surveyed by using the global stability of the corresponding elliptic system ...
Hongtao Zhang, Jingfu Zhao
doaj   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

On an Analogy of Fermat’s Theorem for the First-Level General Fractional Derivative and Its Applications

Fractal and Fractional
Fermat’s theorem, often referred to as the interior extrema theorem, is one of the fundamental results in calculus and optimization theory. Recently, the statement of this theorem has been generalized to the case of fractional derivatives.
Mohammed Al-Refai, Yuri Luchko
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source