Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Generalized spreading speeds for lattice differential equations with time and space dependence
Electronic Journal of Differential Equations, 2019 This article concerns the spatial spreading speeds for lattice differential equations with general time and space dependence. Firstly, we give the concept of spreading speed intervals.
Ning Wang, Zhi-Cheng Wang
doaj
Existence and Multiplicity of Solutions for a Class of Particular Boundary Value Poisson Equations
Mathematics, 2022 In this paper, a special class of boundary value problems, −▵u=λuq+ur,inΩ,u>0, inΩ,n·∇u+g(u)u=0,on∂Ω, where ...
Songyue Yu, Baoqiang Yan
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Local existence of solutions and comparison principle for initial boundary value problem with nonlocal boundary condition for a nonlinear parabolic equation with memory [PDF]
, 2023 Alexander Gladkov
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Hopf's lemma for a class of singular/degenerate PDE-s
, 2014 This paper concerns Hopf's boundary point lemma, in certain $C^{1,Dini}$-type domains, for a class of singular/degenerate PDE-s, including $p$-Laplacian.
Mikayelyan, Hayk, Shahgholian, Henrik
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Positivity and nonexistence of solutions for quasilinear inequalities
Electronic Journal of Differential Equations, 2016 We prove a positivity property and a nonexistence theorem for weak solutions of quasilinear differential equalities in R^N. To obtain our results, we use a comparison principle.
Xiaohong Li
doaj
Comparison of volume of the forebrain, subarachnoid space and lateral ventricles between dogs with idiopathic epilepsy and controls using a stereological approach: Cavalieri’s principle [PDF]
, 2021 Fraje Watson +5 more
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Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source