Results 51 to 60 of about 2,857,638 (285)

Positivity and nonexistence of solutions for quasilinear inequalities

open access: yesElectronic Journal of Differential Equations, 2016
We prove a positivity property and a nonexistence theorem for weak solutions of quasilinear differential equalities in R^N. To obtain our results, we use a comparison principle.
Xiaohong Li
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Minimal wave speed of traveling wavefronts in delayed Belousov-Zhabotinskii model

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2012
This paper is concerned with the traveling wavefronts of Belousov-Zhabotinskii model with time delay. By constructing proper upper and lower solutions and applying the theory of asymptotic spreading, the minimal wave speed is obtained under the weaker ...
Shuxia Pan, Jie Liu
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

On the Keldys-Fichera boundary-value problem for degenerate quasilinear elliptic equations

open access: yesElectronic Journal of Differential Equations, 2002
We prove existence and uniqueness theorems for the Keldys-Fichera boundary-value problem using pseudo-monotone operators. The equation studied here is quasilinear, elliptic, and its set of degenerate points may be of non-zero measure.
Zu-Chi Chen, Benjin Xuan
doaj  

Oscillation Theorems of Fourth-Order Differential Equations with a Variable Argument Using the Comparison Technique

open access: yesAxioms
In this study, we establish new oscillation criteria for solutions of the fourth-order differential equation (aϕuu‴)+q(u∘h)=0, which is of a functional type with a delay.
Osama Moaaz   +2 more
doaj   +1 more source

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