Results 51 to 60 of about 587,634 (306)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A strong comparison principle for the generalized Dirichlet problem for Monge-Ampere
, 2023 We prove a strong form of the comparison principle for the elliptic Monge-Ampere equation, with a Dirichlet boundary condition interpreted in the viscosity sense.
Hamfeldt, Brittany Froese
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Minimal wave speed of traveling wavefronts in delayed Belousov-Zhabotinskii model
Electronic Journal of Qualitative Theory of Differential Equations, 2012 This paper is concerned with the traveling wavefronts of Belousov-Zhabotinskii model with time delay. By constructing proper upper and lower solutions and applying the theory of asymptotic spreading, the minimal wave speed is obtained under the weaker ...
Shuxia Pan, Jie Liu
doaj +1 more source
Principles of Germplasm Comparisons
Journal of Dairy Science, 1987 Abstract Design of germplasm comparisons depends on the hypothesis to be tested. Most important hypotheses concern the future environment for production and marketing. 1) Will the best bulls in an exotic breed improve a local breed?; 2) Is it efficient to upgrade a local breed with bulls from a related exotic breed that has a large, effective program ...
openaire +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Comparison principle for difference equations with variable-time impulses
, 2018 In this paper, a class of difference equations with variable-time impulses is considered. By applying comparison principle, we shall show that difference equations with variable-time impulse can be reduced to the corresponding difference equations with ...
Chuandong Li, Hongfei Li, Tingwen Huang
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source