Results 41 to 50 of about 587,634 (306)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Principle comparison of between US, DTW and our method.

open access: yes, 2016
Principle comparison of between US, DTW and our method.
Ren Song (3216819)   +1 more
core   +1 more source

A weak comparison principle in tubular neighbourhoods of embedded manifolds

open access: yes, 2020
We study weak solutions to degenerate quasilinear elliptic equations, involving first order terms, in unbounded tubular domains. In particular we show that, under suitable hypotheses, the weak comparison principle holds if the domain is narrow ...
Sabatino P., Polizzi F., Sciunzi B.
core   +1 more source

A comparison principle for nonlinear heat Rockland operators on graded groups [PDF]

open access: yes, 2018
In this note we show a comparison principle for nonlinear heat Rockland operators on graded groups. We give a simple proof for it using purely algebraic relations.
Ruzhansky, M   +3 more
core   +1 more source

Extinction of solutions to a diffusion problem with nonlinear sources and variable density

open access: yesResults in Applied Mathematics, 2022
In this paper, we investigate the extinction of solutions to a diffusion problem with a variable density as follows, (0.1) ρ(x)ut=Δum+ρ(x)u∫Ωupdx(x,t)∈Ω×[0,T),u(x,t)=0(x,t)∈∂Ω×[0,T),u(x,0)=u0(x)x∈Ω.We give some sufficient conditions for the extinction of
Weijie Jiang, Junhui Xie
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Generalized spreading speeds for lattice differential equations with time and space dependence

open access: yesElectronic Journal of Differential Equations, 2019
This article concerns the spatial spreading speeds for lattice differential equations with general time and space dependence. Firstly, we give the concept of spreading speed intervals.
Ning Wang, Zhi-Cheng Wang
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Positivity and nonexistence of solutions for quasilinear inequalities

open access: yesElectronic Journal of Differential Equations, 2016
We prove a positivity property and a nonexistence theorem for weak solutions of quasilinear differential equalities in R^N. To obtain our results, we use a comparison principle.
Xiaohong Li
doaj  

Delayed pitch comparisons and the principle of proximity [PDF]

open access: yesPerception & Psychophysics, 1978
Subjects compared the pitches of two tones which were separated by a retention interval during which six extra tones were interpolated. The effects were studied of varying the sizes of the melodic intervals formed by the successive tones of the interpolated sequence. It was found that error rates were lower when the interpolated sequences were composed
openaire   +2 more sources

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