Results 81 to 90 of about 45,955 (291)

Influence of the Upstream Channel of a Ship Lift on the Hydrodynamic Performance of a Fleet Entry Chamber and Design of Traction Scheme

open access: yesJournal of Marine Science and Engineering
This study investigates the hydrodynamic performance of ships entering a ship lift compartment that is under the influence of upstream channel geometry and proposes a mechanical traction scheme to enhance operational safety and efficiency.
Haichao Chang   +6 more
doaj   +1 more source

Safety of Sodium‐Ion Batteries: Evaluation and Perspective from Component Materials to Cells, Modules, and Packs

open access: yesAdvanced Energy Materials, EarlyView.
This review provides a bottom‐up evaluation of sodium‐ion battery safety, linking material degradation mechanisms, cell engineering parameters, and module/pack assembly. It emphasizes that understanding intrinsic material stability and establishing coordinated engineering control across hierarchical levels are vital for preventing degradation coupling ...
Won‐Gwang Lim   +5 more
wiley   +1 more source

Design implications of the new harmonised probabilistic damage stability regulations [PDF]

open access: yes, 2007
In anticipation of the forthcoming new harmonised regulations for damage stability, SOLAS Chapter II-1, proposed in IMO MSC 80 and due for enforcement in 2009, a number of ship owners and consequentially yards and classification societies are venturing ...
Jasionowski, Andrzej   +4 more
core  

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon   +12 more
wiley   +1 more source

Obesity control by SHIP inhibition requires pan-paralog inhibition and an intact eosinophil compartment [PDF]

open access: gold, 2020
Sandra Fernandes   +10 more
openalex   +3 more sources

Vibration Characteristic Research of 100 m New Polar Exploration Cruise Based on Finite Element Modeling

open access: yesJournal of Marine Science and Engineering
Luxury cruise ships are high-end passenger ships with facilities on board for the leisure and entertainment of passengers, so the comfort of luxury cruise ships is a matter of great concern.
Guohe Jiang   +4 more
doaj   +1 more source

Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats [PDF]

open access: yes, 2017
The aim of this study was to describe the joint pharmacokinetic-pharmacodynamic model and evaluate thermal antinociception of a high-concentration formulation of buprenorphine (Simbadol™) in ...
Beaudry, F   +6 more
core   +3 more sources

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe   +9 more
wiley   +1 more source

Gamma Irradiation of Poly(lactide‐co‐glycolide) Scaffolds Reduces the Mechanical Stability and Function of Islet Grafts in Diabetic Nonhuman Primates

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Clinical islet transplantation has long been investigated as a potential cure for type 1 diabetes (T1D), yet standard intrahepatic delivery leaves islets prone to an instant blood‐mediated inflammatory response. Herein, we investigated the design of microporous poly(D,l‐lactide‐co‐glycolide) (PLG) scaffolds for extrahepatic islet ...
Jessica L. King   +15 more
wiley   +1 more source

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