Results 81 to 90 of about 663,929 (286)

289 Rack curtains improve sailors’ sleeping conditions in berthing compartments of the United States Navy (USN) ships [PDF]

, 2021
Panagiotis Matsangas, Nita Lewis Shattuck, Heather Clifton   +2 more
openalex   +1 more source

MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis [PDF]

, 2016
MicroRNA-155 (miR-155) is an important regulator of B cells in mice. B cells have a critical role in the pathogenesis of rheumatoid arthritis (RA). Here we show that miR-155 is highly expressed in peripheral blood B cells from RA patients compared with ...
Alivernini, Stefano, Benvenuto, Roberta, Canestri, Silvia, Di Mario, Clara, Elmesmari, Aziza, Fedele, Anna Laura, Ferraccioli, Gianfranco, Gigante, Maria Rita, Gremese, Elisa, Kurowska-Stolarska, Mariola, Mangoni, Antonella, McInnes, Iain B., Petricca, Luca, Tolusso, Barbara   +13 more
core   +2 more sources

Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes

Advanced Science, EarlyView.
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo, Josephine A. Robertson, Andrea Aparicio, Kirsten Seale, Qingwen Chen, Anne Richmond, Zhaozhen Du, Mahnoor Sulaiman, Shijie C Zheng, Esteban Ballestar, Charlotte AM Cecil, Bastiaan T Heijmans, Steve Horvath, Varun B. Dwaraka, Jessica Lasky‐Su, Ryan Smith, Riccardo E. Marioni, Andrew E Teschendorff   +17 more
wiley   +1 more source

Breakage assessment of ship structures based on PCA-BOA-KNN model underwater explosions

Zhongguo Jianchuan Yanjiu
ObjectiveTo address the issue of assessing structural breach damage in ships under underwater explosion, a breach prediction method based on the PCA-BOA-KNN model is established.
Xiaodi LIANG, Yindong LIU
doaj   +1 more source

Numerical simulation on anti-explosion performance of cabin composite structure

Zhongguo Jianchuan Yanjiu, 2019
[Objectives] With the development of modern ship technology and the higher requirement for the ship hull's own resistance capability to the anti-ship weapons,the composite materials have been more widely used in warship protective structure.
Wu Guangming, Xu Yadong, Li Zhengguo, Wang Zhikai, Yao Xiongliang   +4 more
doaj   +1 more source

Habitability in Berthing Compartments and Well-Being of Sailors Working on U.S. Navy Surface Ships

Human Factors: The Journal of the Human Factors and Ergonomics Society, 2020
Objective The study had two objectives: (a) to assess the prevalence of sleep-related habitability concerns in the berthing compartments of U.S. Navy surface ships and (b) to assess whether habitability issues in berthing compartments affected the sleep and well-being of crew members.
Panagiotis Matsangas, Nita Lewis Shattuck   +1 more
openaire   +3 more sources

Shear Conditioning Promotes Microvascular Endothelial Barrier Resilience in a Human BBB‐on‐a‐Chip Model of Systemic Inflammation Leading to Astrogliosis

Advanced Science, EarlyView.
Physiological flow (0.5 Pa) conditioning promotes resilience of an iPSC‐derived blood–brain barrier endothelium to mild systemic inflammation. In contrast, high “cytokine storm” levels induce barrier breakdown, fibrinogen leakage, and astrocyte activation, reconstituting the two‐hit injury mechanism on‐a‐chip.
Kaihua Chen, Isabelle M. Linares, Michelle A. Trempel, Alexis M. Feidler, Dinindu De Silva, Sami Farajollahi, Jordan Jones, Julia Kuebel, Pelin Kasap, Britta Engelhardt, Jonathan Flax, Vinay V. Abhyankar, Richard E. Waugh, Harris A. Gelbard, Niccolo Terrando, James L. McGrath   +15 more
wiley   +1 more source

A multi-group SEIRA model for the spread of COVID-19 among heterogeneous populations [PDF]

, 2020
The outbreak and propagation of COVID-19 have posed a considerable challenge to modern society. In particular, the different restrictive actions taken by governments to prevent the spread of the virus have changed the way humans interact and conceive ...
Biron-Lattes, Juan Pablo, Contreras, Sebastian, Medina-Ortiz, David, Olivera-Nappa, Alvaro, Villavicencio, H. Andres   +4 more
core   +2 more sources

Aging as a Loss of Goal‐Directedness: An Evolutionary Simulation and Analysis Unifying Regeneration with Anatomical Rejuvenation

Advanced Science, EarlyView.
The paper proposes that the root cause of aging is the loss of anatomical goal‐directedness after development. Using evolutionary neural cellular automata simulations, the authors show that after the organism has reached its developmental homeostatic setpoint (the adult morphology), the absence of target state to pursue leads to a drifting anatomical ...
Léo Pio‐Lopez, Benedikt Hartl, Michael Levin   +2 more
wiley   +1 more source

Influence of the Upstream Channel of a Ship Lift on the Hydrodynamic Performance of a Fleet Entry Chamber and Design of Traction Scheme

Journal of Marine Science and Engineering
This study investigates the hydrodynamic performance of ships entering a ship lift compartment that is under the influence of upstream channel geometry and proposes a mechanical traction scheme to enhance operational safety and efficiency.
Haichao Chang, Qiang Zheng, Zuyuan Liu, Yu Yao, Xide Cheng, Baiwei Feng, Chengsheng Zhan   +6 more
doaj   +1 more source