Results 71 to 80 of about 44,422 (248)

Mapping opioid exposure through prescription data and postmortem analysis of opioid drugs in multiple tissues

British Journal of Clinical Pharmacology, EarlyView.
Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins, Alan Wells, Nimish Patel, Nicole Muttera, Mattia Trunfio, Alessandra Manca, Amedeo De Nicolò, Micol Ferrara, Stefano Bonora, Jessica Cusato, Alice Palermiti, Antonio D'Avolio, Marissa Borochoff, Patricia K. Riggs, Elizabeth Hastie, Rabia S. Atayee, Stephanie Solso, Cheryl Dullano, Vanessa Gomez‐Moreno, Tara Tenenbaum, Robert Deiss, Davey M. Smith, Antoine Chaillon, Sara Gianella   +23 more
wiley   +1 more source

Numerical simulation on anti-explosion performance of cabin composite structure

Zhongguo Jianchuan Yanjiu, 2019
[Objectives] With the development of modern ship technology and the higher requirement for the ship hull's own resistance capability to the anti-ship weapons,the composite materials have been more widely used in warship protective structure.
Wu Guangming, Xu Yadong, Li Zhengguo, Wang Zhikai, Yao Xiongliang   +4 more
doaj   +1 more source

Numerical Simulations on the Flooding into a Damaged Cabin with a Flexible Bulkhead Based on the Mixed-Mode Function-Modified MPS Method

Journal of Marine Science and Engineering, 2022
Floodwater entering the damaged cabin and impacting the bulkhead can cause damage to the watertight compartment and affect the survival of the ship. The elastic deformation of the bulkhead can slow down the impact and affect the flow field, which affects
Jinxin Wu, Guiyong Zhang, Yichen Jiang, Xi Yang   +3 more
doaj   +1 more source

Erectable modular space station Patent [PDF]

, 1965
Manned space station collapsible for launching and self-erectable in ...
Berglund, R. A.
core   +1 more source

Rapid killing of bed bugs (Cimex lectularius L.) on surfaces using heat: application to luggage. [PDF]

, 2016
BackgroundThe resistance of bed bugs (Cimex lectularius L.) to chemical insecticides has motivated the development of non-chemical control methods such as heat treatment.
Loudon, Catherine
core   +2 more sources

Modeling fires in adjacent ship compartments with computational fluid dynamics [PDF]

, 1998
This paper presents an analysis of the thermal effects on radioactive (RAM) transportation packages with a fire in an adjacent compartment. An assumption for this analysis is that the adjacent hold fire is some sort of engine room fire. Computational fluid dynamics (CFD) analysis tools were used to perform the analysis in order to include convective ...
Wix, S. D., Cole, J. K., Koski, J. A.
openaire   +2 more sources

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

British Journal of Clinical Pharmacology, EarlyView.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong, Luisa Rojas Chavarro, Paul Jones, David Egging, Wanchana Ungphakorn, Marta Valle, Ivan Matthews   +6 more
wiley   +1 more source

Study of the mass transfer phenomena involved in an electrophoretic membrane contactor [PDF]

, 2001
Electrophoretic separators, in which a porous membrane is used as a contactor, offer the possibility to scale up electrophoresis as well as to extend the field of application of electrodialysis to fractionate polyamino acids, peptides or small proteins ...
Galier, Sylvain, Roux-de Balmann, Hélène   +1 more
core   +2 more sources

Clinical and Radiometabolic Correlatives of ddPCR Liquid Biopsy for BRAF V600 Mutated Melanoma

International Journal of Cancer, EarlyView.
Commercial circulating tumor DNA (ctDNA) liquid biopsy tests are increasingly used for disease monitoring and surveillance in melanoma. However, data regarding the possible correlations between ctDNA and baseline clinical and radiometabolic parameters such as metastatic locations, tumor volume, and tumor glycolysis in patients with BRAF‐mutated ...
Ronen Stoff, Gokce Belge Bilgin, Yalda Nikanpour, Geoffrey B. Johnson, Benjamin R. Kipp, David M. Zahrieh, Katherine B. Geiersbach, Matthew S. Block, Svetomir N. Markovic   +8 more
wiley   +1 more source

Vibration Characteristic Research of 100 m New Polar Exploration Cruise Based on Finite Element Modeling

Journal of Marine Science and Engineering
Luxury cruise ships are high-end passenger ships with facilities on board for the leisure and entertainment of passengers, so the comfort of luxury cruise ships is a matter of great concern.
Guohe Jiang, Yuhao Yuan, Hao Guo, Gang Wu, Zhenzhen Liu   +4 more
doaj   +1 more source