Results 41 to 50 of about 10,794 (263)
Revista de la Facultad de Ciencias Agrarias, 2020 A correct selection of salt-tolerant plants should consider the relative effects of the various existing tolerance mechanisms. When toxic ions, like Na+, reach the leaves, they affect the photosynthetic apparatus, reducing plant growth and ...
Hernán F. Vila +4 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FireThis article focuses on the fire safety risks associated with conventional glass–aluminum façades—with a particular focus on stick and unitized curtain walling systems—providing an overview of possible fire spread mechanisms, considering the role of the ...
Arritokieta Eizaguirre-Iribar +3 more
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Horticulture Research, 2019 In developing apple fruit, metabolic compartmentation is poorly understood due to the lack of experimental data. Distinguishing subcellular compartments in fruit using non-aqueous fractionation has been technically difficult due to the excess amount of ...
Wasiye F. Beshir +6 more
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Alterations of cAMP-dependent signaling in dystrophic skeletal muscle
Frontiers in Physiology, 2013 Autonomic regulation processes in striated muscles are largely mediated by cAMP/PKA-signaling. In order to achieve specificity of signaling its spatial-temporal compartmentation plays a critical role. We discuss here how specificity of cAMP/PKA-signaling
Rüdiger eRudolf +6 more
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Tight coupling of Na+/K+-ATPase with glycolysis demonstrated in permeabilized rat cardiomyocytes. [PDF]
PLoS ONE, 2014 The effective integrated organization of processes in cardiac cells is achieved, in part, by the functional compartmentation of energy transfer processes.
Mervi Sepp +5 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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Studying GPCR/cAMP pharmacology from the perspective of cellular structure
Frontiers in Pharmacology, 2015 Signal transduction via G-protein coupled receptors (GPCRs) relies upon the production of cAMP and other signaling cascades. A given receptor and agonist pair, produce multiple effects upon cellular physiology which can be opposite in different cell ...
Peter T Wright +2 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
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