Results 21 to 30 of about 222,490 (305)

In Vitro and Clinical Compassionate Use Experiences with the Drug-Repurposing Approach CUSP9v3 in Glioblastoma

open access: yesPharmaceuticals, 2021
Background: Glioblastoma represents the most common primary brain tumor in adults. Despite technological advances, patients with this disease typically die within 1–2 years after diagnosis.
Marc-Eric Halatsch   +8 more
doaj   +1 more source

Compassion in emergency departments. Part 1: nursing students’ perspectives [PDF]

open access: yes, 2018
Compassion is a topical issue in clinical nursing practice, nurse education and policy, but a review of the literature reveals that nursing students’ experiences of compassionate care receives little attention.
Howes, Dora   +2 more
core   +3 more sources

Phage Therapy in the 21st Century: Is There Modern, Clinical Evidence of Phage-Mediated Efficacy?

open access: yesPharmaceuticals, 2021
Many bacteriophages are obligate killers of bacteria. That this property could be medically useful was first recognized over one hundred years ago, with 2021 being the 100-year anniversary of the first clinical phage therapy publication. Here we consider
Stephen T. Abedon   +2 more
doaj   +1 more source

Compassionate Treatment of Brainstem Tumors with Boron Neutron Capture Therapy: A Case Series

open access: yesLife, 2022
Brainstem tumors are heterogenous and cancerous glioma tumors arising from the midbrain, pons, and the medulla that are relatively common in children, accounting for 10% to 20% of all pediatric brain tumors. However, the prognosis of aggressive brainstem
Yi-Wei Chen   +31 more
doaj   +1 more source

A qualitative exploration of responses to self-compassion in a non-clinical sample [PDF]

open access: yes, 2016
Research suggests that being self-compassionate can have myriad benefits, including life satisfaction, health-promoting behaviours and improved mental health.
Campion, Maxine, Glover, Lesley
core   +1 more source

Real‐world treatment outcomes of medicines used in special situations (off‐label and compassionate use) in oncology and hematology: A retrospective study from a comprehensive cancer institution

open access: yesCancer Medicine, 2023
Purpose Medicines in special situations (MSS) refer to off‐label or to unlicensed drugs under investigation (compassionate use). Our objectives were to evaluate characteristics and to estimate overall survival (OS), event‐free survival (EFS), and the ...
Sandra Fontanals   +6 more
doaj   +1 more source

Compassionate Use of Ripretinib for Patients With Metastatic Gastrointestinal Stromal Tumors: Taiwan and Hong Kong Experience

open access: yesFrontiers in Oncology, 2022
BackgroundRipretinib was recently approved for the fourth-line targeted therapy for advanced gastrointestinal stromal tumor (GIST) refractory to imatinib, sunitinib, and regorafenib based on the pivotal INVICTUS phase III study.
Li-Ching Lin   +10 more
doaj   +1 more source

Essential Topics for the Regulatory Consideration of Phages as Clinically Valuable Therapeutic Agents: A Perspective from Spain

open access: yesMicroorganisms, 2022
Antibiotic resistance is one of the major challenges that humankind shall face in the short term. (Bacterio)phage therapy is a valuable therapeutic alternative to antibiotics and, although the concept is almost as old as the discovery of phages, its wide
Roberto Vázquez   +10 more
doaj   +1 more source

Compassion on University Degree Programmes at a UK University: The Neuroscience of Effective Group work [PDF]

open access: yes, 2018
This article is published under the Creative Commons Attribution (CC BY 4.0) licence. Anyone may reproduce, distribute, translate and create derivative works of this article (for both commercial and non-commercial purposes), subject to full attribution ...
Beka, Dr Sylvia   +5 more
core   +3 more sources

Taking AIM at serious illness: implementing an access to investigational medicines expanded access program

open access: yesFrontiers in Medicine, 2023
When seriously ill patients have exhausted all treatment options available as part of usual care, the use of investigational agents may be warranted. Food and Drug Administration’s (FDA) Expanded Access (EA) pathway provides a mechanism for these patient’
Meghan Morrison Joly   +5 more
doaj   +1 more source

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