Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Coincidence and fixed points for compatible and relatively nonexpansive maps
International Journal of Mathematics and Mathematical Sciences, 1993 The concept of relatively nonexpansive maps is introduced. Fixed point and coincidence results for families of four self maps of metric spaces are obtained.
Gerald Jungck
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
On a fixed point theorem of Fisher and Sessa
International Journal of Mathematics and Mathematical Sciences, 1990 A fixed point theorem of Fisher and Sessa is generalized by replacing the requirements of commutativity and nonexpansiveness by compatibility and continuity respectively.
Gerald Jungck
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Fixed Points of Weakly Compatible Maps Satisfying a General Contractive Condition of Integral Type
Fixed Point Theory and Applications, 2007 We prove a fixed point theorem for weakly compatible maps satisfying a general contractive condition of integral type.
Ishak Altun +2 more
doaj +2 more sources
A common fixed point theorem in Menger space using implicit relation [PDF]
Surveys in Mathematics and its Applications, 2013 The main purpose of this paper is to prove a common fixed point theorem for two pairs of weakly compatible mappings in Menger space using implicit relation.
B.D. Pant, Sunny Chauhan
doaj
Weak contractive integral inequalities and fixed points in modular metric spaces
Journal of Inequalities and Applications, 2016 Branciari (Int. J. Math. Math. Sci. 29(9):531-536, 2002) gave an interesting supplement of Banach’s contraction principle for an integral-type inequality.
Nawab Hussain +3 more
doaj +1 more source
Common fixed points for commuting and compatible maps on compacta
, 1988 Compatible maps—a generalization of commuting maps—are characterized in terms of coincidence points, and common fixed point theorems for compatible maps and commuting maps on compact metric spaces are obtained.
Gerald Jungck
core +1 more source