Results 51 to 60 of about 4,087 (207)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Sub-compatible maps and common fixed point theorem in non-Archimedean Menger PM-space

open access: yes, 2020
The object of this paper is to establish common fixed point theorems for four self maps using the concepts of compatible maps, sub-sequential continuous ...
Arihant Jain   +2 more
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Compatibility support mappings in effect algebras [PDF]

open access: yesMathematica Slovaca, 2012
Abstract We give a characterization of subsets of effect algebras, that can be embedded into a range of an observable. To give this characterization, we introduce a new notion of compatibility support mappings.
openaire   +3 more sources

Coincidences and fixed points of reciprocally continuous and compatible hybrid maps

open access: yes, 2002
It is proved that a pair of reciprocally continuous and nonvacuously compatible single-valued and multivalued maps on a metric space possesses a coincidence.
S. N. Mishra, S. L. Singh
core   +1 more source

In vivo functional and myeloarchitectonic mapping of human primary auditory areas [PDF]

open access: yes, 2012
In contrast to vision, where retinotopic mapping alone can define areal borders, primary auditory areas such as A1 are best delineated by combining in vivo tonotopic mapping with postmortem cyto- or myeloarchitectonics from the same individual.
Dick, Frederic   +9 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

FIXED POINT THEOREM IN FUZZY METRIC SPACES FOR NON-COMPATIBLE AND WEAKLY COMPATIBLE MAPS

open access: yes, 2015
In this paper, the concept of both weakly compatible and non-compatible maps has been applied to prove common fixed point theorem in fuzzy metric spaces.  A fixed point theorem for five maps has been established.
Sharma, Mami
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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