Results 51 to 60 of about 1,516,946 (302)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Common Fixed Point Theorems in Menger Probabilistic Quasimetric Spaces
Fixed Point Theory and Applications, 2009 We consider complete Menger probabilistic quasimetric space and prove common fixed point theorems for weakly compatible maps in this space.
Shaban Sedghi +2 more
doaj +2 more sources
Coincidences and fixed points of reciprocally continuous and compatible hybrid maps
International Journal of Mathematics and Mathematical Sciences, 2002 It is proved that a pair of reciprocally continuous and nonvacuously compatible single-valued and multivalued maps on a metric space possesses a coincidence.
S. L. Singh, S. N. Mishra
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Map-compatible decomposition of transport paths
, 2023 In the Monge-Kantorovich transport problem, the transport cost is expressed in terms of transport maps or transport plans, which play crucial roles there. A variant of the Monge-Kantorovich problem is the ramified (branching) transport problem that models branching transport systems via transport paths.
Xia, Qinglan, Sun, Haotian
openaire +2 more sources
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Common fixed point theorem for noncompatible maps in probabilistic metric space [PDF]
Surveys in Mathematics and its Applications, 2013 In this paper, we prove a common fixed point theorem for noncompatible maps in probabilistic metric space using implicit relation. Our result does not require either the completeness of the space or continuity of the maps.
Suneel Kumar, Sunny Chauhan, B. D. Pant
doaj