Results 61 to 70 of about 20,620 (307)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Design of a Controller to Overcome Air Ball in the Ball-on-plate System Applied to a Shelf Cart [PDF]
한국정밀공학회지A ball-on-plate system is a mechanical control system for measuring the position of a ball placed on a touch panel and controlling the ball to move to a desired position. This system has been applied to a shelf cart.
Sangsin Park
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Implementation of cascade type PIS compensator for pneumatic anti-vibration apparatuses
Nihon Kikai Gakkai ronbunshu, 2018 This paper considers the implementation of a cascade type PIS compensator for the pneumatic anti-vibration apparatuses (AVA) control system. In precedence research the parallel type PIS compensator was used.
Ryoya TANAKA, Shinji WAKUI
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
, 2018 General-compensation-purpose Static var Compensator ...
Eduardo Verri Liberado +1 more
core +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Two-Stage Compensator Designs with Partial Feedbacks
, 2012 The two-stage compensator designs of linear system are investigated in the framework of the factorization approach. First, we give "full feedback" two-stage compensator design. Based on this result, various types of the two-stage compensator designs with
Kazuyoshi MORI
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
, 2016 Single Wire Earth Return (SWER) system with long transmission line is introduced as one method for low cost remote electrification. Long transmission line and load growth can makes voltage regulation a concern.
Ahfock, Tony +5 more
core +1 more source