Results 111 to 120 of about 2,857,057 (386)

Confidence and Competence in Communication [PDF]

open access: yes, 2012
This paper studies information transmission between an uninformed decision maker (receiver) and an informed player (sender) who have asymmetric beliefs ("confidence") on the sender’s ability ("competence") to observe the state of ...
Kawamura, Kohei
core   +4 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Synthesis and Characterization of Imidazolium-Based Ionenes

open access: yesMolecules
Owing to multiple non-covalent interactions, ionic groups impart unique chemical and physical properties into polymers including ion conductivity/mobility, permeation, and intrinsic healability.
Eveline Elisabeth Kanatschnig   +3 more
doaj   +1 more source

Fragebogenkonstruktion zur Evaluation von Praktikabilität und Nutzen des Bundeseinheitlichen Medikationsplans

open access: yesGMS Medizinische Informatik, Biometrie und Epidemiologie, 2017
With the formulation of a claim for a national uniform medication plan, the German government has taken an important step towards optimizing the documentation of medication for multimorbid patients.
Thoma, Martin   +3 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Reducing behaviour problems in young people through social competence programmes [PDF]

open access: yes, 2010
There is a relatively strong relationship between the concepts of behavioural problems and social competence, in that social competence is regarded as one of the most important protective factors in the prevention of behavioural problems.
Gundersen, Knut K.
core   +2 more sources

Rapamycin improves the developmental competence of human oocytes by alleviating DNA damage during IVM

open access: gold, 2022
Qiyu Yang   +7 more
openalex   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

open access: yesFEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey   +2 more
wiley   +1 more source

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