Results 191 to 200 of about 2,857,057 (386)

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

Academic achievement of peer group leaders and members: Contributions to adolescents' social, school, and psychological adjustment. [PDF]

J Res Adolesc
Zhou J, Chen X, Li D, Liu J, Cui L, Liu S.   +5 more
europepmc   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Lean-proteome strains – next step in metabolic engineering

Frontiers in Bioengineering and Biotechnology, 2015
Kaspar eValgepea, Karl ePeebo, Karl ePeebo, Kaarel eAdamberg, Kaarel eAdamberg, Raivo eVilu, Raivo eVilu   +6 more
doaj   +1 more source

Cell density and single-cell heterogeneity reveal distinct competence induction dynamics in the high-GC Gram-positive Micrococcus luteus. [PDF]

BMC Microbiol
Lichev A, Angelov A, Liebl W.
europepmc   +1 more source

Pioneering the Future: Principles, Advances, and Challenges in Organic Electrodes for Aqueous Ammonium‐Ion Batteries

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
Leveraging the numerous advantages of ammonium‐ion (NH₄⁺)—including cost‐effectiveness, low corrosiveness, preferential orientation, and rapid diffusion kinetics—aqueous NH₄⁺ batteries (AAIBs) have gained significant attention. This review highlights and evaluates the progress of AAIBs utilizing organic electrode materials such as small molecules ...
Mangmang Shi, Xiaoyan Zhang
wiley   +1 more source

Individuals Adjust Their Degree of Advice Taking to Impress Others. [PDF]

Psych J
Du X, Wu S, Li R, Ren F.
europepmc   +1 more source

Competence Modelling, Competence Models and Competence Development - an Overview

, 2011
This paper will summarize the potential use cases and impacts of competences and skills in the new area, often called "Digital Age": It will highlight the roles and benefits of standards and metadata for HR development and points out the special support that competence models can provide for the quality development in learning, education, and training.
openaire   +2 more sources

Giga‐Voxel Multiscale Composite Architecture Mirrored Through a Data‐to‐Model Closed‐Loop Digital Twin

Advanced Materials, EarlyView.
Herein, a systematic digital twin workflow tailored for generating high‐fidelity virtual representations of anisotropic composite microstructures and giga‐voxel meso‐structural models is presented, leveraging a harmonious integration of top–down image‐based modeling and bottom–up data‐driven voxel generation.
Siwon Yu, Seungsoo Jang, Young Seok Cho, Seunggyu Park, Jun Yeon Hwang, Soon Hyung Hong, Thomas James Marrow, Kang Taek Lee   +7 more
wiley   +1 more source

Digital competence for sustainable education of pre-service teachers: a systematic literature review (2014-2024). [PDF]

Front Psychol
Zhang L, Yang C, Zheng Y.
europepmc   +1 more source