Results 231 to 240 of about 992,860 (360)
AntiBMPNN: Structure‐Guided Graph Neural Networks for Precision Antibody Engineering
AntiBMPNN, a deep learning framework that integrates antibody‐specific 3D data, MPNN, frequency‐based scoring, and AlphaFold 3, achieves superior antibody sequence design. In most cases, it outperforms ProteinMPNN, AntiFold, and AbMPNN in CDR design, demonstrating higher binding affinities and sequence recovery.
Ze‐Yu Sun+13 more
wiley +1 more source
Motivation, psychological needs and physical activity in older adults: a qualitative review. [PDF]
Palombi T+12 more
europepmc +1 more source
La Cour Supreme et le Partage des Competences Legislatives
Gérald A. Beaudoin
openalex +2 more sources
While cognitive development typically exhibits differentiation, marked by decreasing inter‐domain correlations, this study demonstrates that five‐year abacus training is associated with de‐differentiation of executive function and mathematical ability in school‐aged children.
Tianyong Xu+5 more
wiley +1 more source
Teacher-student relationship quality and social, academic, and behavioral adjustment are associated within and between persons from kindergarten to grade 6. [PDF]
Magro SW+3 more
europepmc +1 more source
DSBs are the most critical genomic lesions. Using the ChromInSight framework, It is revealed that 3D chromatin structure, rather than linear distance, shapes cluster‐scene between hub‐Nodes and DSB loci. The “spatial isolation–damage containment” hypothesis is proposed to illustrate how the genome responds to genomic damage and offer a powerful tool ...
Kang Xu+9 more
wiley +1 more source
Taking a Closer Look at Teacher Support and Children's Mental Health: The Mediating Role of Self-Concept and the Moderating Role of Area. [PDF]
Chen Z, Du Q, de Castro BO, Liu G.
europepmc +1 more source
SummaryThis study constructs a single‐cell immune atlas of Nile tilapia across multiple time points during Streptococcus agalactiae infection, revealing dynamic immune cell responses and subtype transitions. It identifies a conserved IFNr‐STAT1‐IL8 axis driving il8+ neutrophils activation and antibacterial function, supported by cross‐species ...
Xue Zhai+14 more
wiley +1 more source