Results 31 to 40 of about 365,678 (170)

Heterogeneity in an adeno-associated virus transfection-based production process limits the production efficiency

Scientific Reports
The popularity of rAAV vectors in gene therapy are placing a burden on current production systems. To improve the accessibility of these life changing treatments, increases in production yields and a reduction in the cost-of-goods are needed.
Brian Ladd, Sofia Tunmats, Torbjörn Gräslund, Olalekan Daramola, Johan Rockberg, Véronique Chotteau   +5 more
doaj   +1 more source

DNA methylation changes in endometrium and correlation with gene expression during the transition from pre-receptive to receptive phase

Scientific Reports, 2017
The inner uterine lining (endometrium) is a unique tissue going through remarkable changes each menstrual cycle. Endometrium has its characteristic DNA methylation profile, although not much is known about the endometrial methylome changes throughout the
Viktorija Kukushkina, Vijayachitra Modhukur, Marina Suhorutšenko, Maire Peters, Reedik Mägi, Nilufer Rahmioglu, Agne Velthut-Meikas, Signe Altmäe, Francisco J. Esteban, Jaak Vilo, Krina Zondervan, Andres Salumets, Triin Laisk-Podar   +12 more
doaj   +1 more source

Lessons learned: overcoming common challenges in reconstructing the SARS-CoV-2 genome from short-read sequencing data via CoVpipe2 [version 2; peer review: 2 approved]

F1000Research
Background Accurate genome sequences form the basis for genomic surveillance programs, the added value of which was impressively demonstrated during the COVID-19 pandemic by tracing transmission chains, discovering new viral lineages and mutations, and ...
Martin Hölzer, Stephan Fuchs, René Kmiecinski, Kathrin Trappe, Marie Lataretu, Oliver Drechsel   +5 more
doaj   +1 more source

Dynamics of the Apple Fruit Microbiome after Harvest and Implications for Fruit Quality

Microorganisms, 2021
The contribution of the apple microbiome to the production chain of apple was so far largely unknown. Here, we describe the apple fruit microbiome and influences on its composition by parameters such as storage season, storage duration, storage ...
Yvonne Bösch, Elisabeth Britt, Sarah Perren, Andreas Naef, Jürg E. Frey, Andreas Bühlmann   +5 more
doaj   +1 more source

Children’s Participation: Questioning Competence and Competencies?

Social Inclusion, 2017
While Article 12 of the Convention on the Rights of the Child has encouraged children’s participation in collective decision-making, the literature is replete with the challenges as well as successes of such participation. One challenge is adults’ perceptions of children’s competence and competencies. These are frequently used as threshold criteria, so
Le borgne, Carine, Tisdall, E Kay M; id_orcid 0000-0001-8967-6426   +1 more
openaire   +3 more sources

Management and outcomes among patients with hard-to-heal ulcers in Sweden: a national mapping of data from medical records, focusing on diagnoses, ulcer healing, ulcer treatment time, pain and prescription of analgesics and antibiotics

BMJ Open
Objective To investigate whether patients with hard-to-heal ulcers in Sweden were treated according to an aetiological diagnosis and to explore ulcer healing, treatment time, ulcer-related pain and the prescription of analgesics and antibiotics.Design A ...
Rut Frank Öien, Maria Boström, Hanna Linnea Wickström, Jenny Roxenius   +3 more
doaj   +1 more source

Oral health and use of dental services in early adulthood and changes from adolescence - Fit Futures, a longitudinal cohort study

BMC Oral Health
Background The journey from adolescence to adulthood brings major life changes that can impact oral health and the utilisation of dental health services. Nevertheless, few longitudinal studies have followed oral health during this transition.
Elin Hadler-Olsen, Therese Bondø, Liv Marit Bergli, Andreas Schmalfuss, Hege Nermo   +4 more
doaj   +1 more source

Pragmatic Competence*

, 2020
Chapter to be included in the volume Routledge Handbook of Skill and Expertise, Eds. Ellen Fridland and Carlotta Pavese, Springer 2020.
Filippo Domaneschi, Valentina Bambini
openaire   +4 more sources

Linguistic competence, Communicative Competence and Interactional Competence

INTERNATIONAL JOURNAL OF COMPUTERS & TECHNOLOGY, 2019
Linguistic competence, communicative competence, and interactional competence have had profound impact on second language teaching, learning, and testing. Although a significant number of studies have been conducted on these three competences, they have not been conflated for discussion in a single study.
Nishad Chathamkulam Abdulrahman, Emad A. S. Abu- Ayyash   +1 more
openaire   +2 more sources

Pixel-Wise Defect Detection by CNNs without Manually Labeled Training Data

Applied Artificial Intelligence, 2019
In machine learning driven surface inspection one often faces the issue that defects to be detected are difficult to make available for training, especially when pixel-wise labeling is required.
M. Haselmann, D. P. Gruber
doaj   +1 more source