Results 51 to 60 of about 1,012,717 (310)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Religious competence as cultural competence [PDF]

Transcultural Psychiatry, 2012
Definitions of cultural competence often refer to the need to be aware and attentive to the religious and spiritual needs and orientations of patients. However, the institution of psychiatry maintains an ambivalent attitude to the incorporation of religion and spirituality into psychiatric practice.
openaire   +2 more sources

Rethinking assessment of competence within a first year nursing science module [PDF]

, 2011
The project evaluated an innovative assessment tool that was developed to provide evidence that students were developing science-informed competence for nursing.
Stewart, Jane, Stewart, Angela
core   +1 more source

Heterogeneity in an adeno-associated virus transfection-based production process limits the production efficiency

Scientific Reports
The popularity of rAAV vectors in gene therapy are placing a burden on current production systems. To improve the accessibility of these life changing treatments, increases in production yields and a reduction in the cost-of-goods are needed.
Brian Ladd, Sofia Tunmats, Torbjörn Gräslund, Olalekan Daramola, Johan Rockberg, Véronique Chotteau   +5 more
doaj   +1 more source

DLMS over Wi-SUN FAN Networks: Performance Evaluation

Applied Sciences
The DLMS (Device Language Message Specification) standard is widely adopted in smart metering systems for utility services, as it defines the mechanisms that enable the standardized and interoperable exchange of data between metering devices. Wi-SUN FAN (
Ananias Ambrosio Quispe, William Lopes de Oliveira, Giancarlo Covolo Heck, Luciana Michelotto Iantorno, Patryk Henrique da Fonseca, Rodrigo Jardim Riella   +5 more
doaj   +1 more source

DNA methylation changes in endometrium and correlation with gene expression during the transition from pre-receptive to receptive phase

Scientific Reports, 2017
The inner uterine lining (endometrium) is a unique tissue going through remarkable changes each menstrual cycle. Endometrium has its characteristic DNA methylation profile, although not much is known about the endometrial methylome changes throughout the
Viktorija Kukushkina, Vijayachitra Modhukur, Marina Suhorutšenko, Maire Peters, Reedik Mägi, Nilufer Rahmioglu, Agne Velthut-Meikas, Signe Altmäe, Francisco J. Esteban, Jaak Vilo, Krina Zondervan, Andres Salumets, Triin Laisk-Podar   +12 more
doaj   +1 more source

Assessment of Epoxy Functionalized Poly(dimethylsiloxane) Vitrimers Catalyzed with Covalently Attached Amines as Reversible Adhesives

Macromolecular Materials and Engineering, 2022
In this work, vitrimeric elastomers based on functionalized poly(dimethylsiloxane) are realized. By exploiting reactions of epoxide functional groups with carboxylic acids in the presence of a covalently bonded amine catalyst, dynamic networks are formed
Florian Wanghofer, Archim Wolfberger, Gernot Oreski, Sandra Schlögl   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The Conflation of Competence and Capacity in English Medical Law: A Philosophical Critique

, 2005
Ethical and legal discourse pertaining to the ability to consent to treatment and research in England operates within a dualist framework of "competence" and "capacity".
Bielby, Philip
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source