Results 71 to 80 of about 752,600 (318)

Aspects of competence-based education as footholds to improve the connectivity between learning in school and in the workplace

, 2010
Recent developments in competence-based education have motivated institutions of vocational education and training (VET) to improve the links or connectivity between learning in school and learning in the workplace, which has been a problem for decades ...
de Jong, C., Wesselink, R., Jong, C., de, Biemans, H.J.A.   +3 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Developing operational competence in purchasing [PDF]

This paper contributes to the emerging theory of purchasing competence. First, it replicates and cross-validates the construct with five underlying supply-side competence dimensions of Narasimhan, Jayaram and Carter (2001), using telephone survey data ...
Done, Adrian
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Oral health and use of dental services in early adulthood and changes from adolescence - Fit Futures, a longitudinal cohort study

BMC Oral Health
Background The journey from adolescence to adulthood brings major life changes that can impact oral health and the utilisation of dental health services. Nevertheless, few longitudinal studies have followed oral health during this transition.
Elin Hadler-Olsen, Therese Bondø, Liv Marit Bergli, Andreas Schmalfuss, Hege Nermo   +4 more
doaj   +1 more source

Information Competence Summer Fellowships

, 1999
In response to the Council of Library Directors' Strategic Plan, the Commission on Learning Resources and Instructional Technology launched a program of information competence in the CSU. In 1995, the Information Competence Work Group was appointed to "..
Curzon, Susan Carol, California State University Information Competence Work Group   +1 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Time perspective and well-being: Swedish survey questionnaires and data

Data in Brief, 2016
The data pertains 448 Swedes’ responses to questionnaires on time perspective (Zimbardo Time Perspective Inventory), temporal life satisfaction (Temporal Satisfaction with Life Scale), affect (Positive Affect and Negative Affect Schedule), and ...
Danilo Garcia, Ali Al Nima, Erik Lindskär   +2 more
doaj   +1 more source

Mental Competence and End-of-Life Decision Making: Death Row Volunteering and Euthanasia

, 2004
This article reports on a qualitative study of defense attorneys' perceptions of the mental competence or rationality of death row inmates' decisions to waive habeas appeals and proceed directly to execution.
Harrington, C. Lee, C. Lee Harrington
core   +1 more source