Results 71 to 80 of about 2,577,512 (424)
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
Ambiguities and paradoxes in a competence-based approach to vocational education and training in France [PDF]
This article aims to show the effects of the prevalence of the competence regime within several sectors of vocational education and training in France.
Hébrard, Pierre
core +2 more sources
BackgroundGross motor competence confers health benefits, but levels in children and adolescents are low. While interventions can improve gross motor competence, it remains unclear which correlates should be targeted to ensure interventions are most ...
L. Barnett+12 more
semanticscholar +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Temporomandibular disorders in an adult population in northern Norway: A cross‐sectional study
Objectives The aim of the study was to assess the prevalence of symptoms indicative of temporomandibular disorders (TMD) in an adult population in Troms County in Northern Norway, as well as the associations between TMD and socio‐demographic factors ...
Elin Hadler‐Olsen+5 more
doaj +1 more source
BACKGROUND Manifestations of core social deficits in autism are more pronounced in everyday settings than in explicit experimental tasks. To bring experimental measures in line with clinical observation, we report a novel method of quantifying atypical ...
A. Klin+4 more
semanticscholar +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Time perspective and well-being: Swedish survey questionnaires and data
The data pertains 448 Swedes’ responses to questionnaires on time perspective (Zimbardo Time Perspective Inventory), temporal life satisfaction (Temporal Satisfaction with Life Scale), affect (Positive Affect and Negative Affect Schedule), and ...
Danilo Garcia+2 more
doaj +1 more source
Competence of bachelor in electromechanics in simulation [PDF]
The article is devoted to communication competence in modeling with other competences of Bachelor in Electromechanics, its structure and the contribution of components in the formation of competence. The approaches to defining competence of bachelor-electrician are determined. A system of competencies is suggested.
arxiv
Competence-Based Student Modelling with Dynamic Bayesian Networks [PDF]
We present a general method for using a competences map, created by defining generalization/specialization and inclusion/part-of relationships between competences, in order to build an overlay student model in the form of a dynamic Bayesian network in which conditional probability distributions are defined per relationship type.
arxiv