Results 41 to 50 of about 1,368,769 (288)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

BASES OF COMPETENCE APPROACH IN COMPUTER SCIENCE TEACHER TRAINING

Інформаційні технології і засоби навчання, 2010
In the article the analysis of methodological and theoretical bases of competence approach has been made. It is given the structure and classification of computer science teacher competences.
Kateryna R. Kovalska
doaj  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Actualization of the concept “competence”, “competency”, “competence approach” in the conditions of integration of science and education

Неофилология, 2015
A short review of use of relevant terms in modern science: competence, competency and competence approach with the aim of defining the author’s relation is given.
Ainagul Bektasovna TUMANOVA
doaj  

When employer brand image aids employee satisfaction and engagement [PDF]

, 2017
Purpose – The purpose of this paper is to test whether employee characteristics (age, gender, role and experience) influence the effects of employer brand image, for warmth and competence, on employee satisfaction and engagement.
Davies, Gary, Mete, Melisa, Whelan, Susan   +2 more
core   +3 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

MODERN ACTIVE AND INTERACTIVE METHODS AS A MEANS OF OPTIMIZING FOREIGN LANGUAGE TEACHING IN NON-LANGUAGE FACULTIES

Вестник Северо-Кавказского федерального университета, 2022
The process of continuous improvement of the educational system invariably entails changes and optimization of methods and forms of organization of the educational process.
V. Plaksin
doaj  

Antimicrobial stewardship: a competency-based approach [PDF]

JAC-Antimicrobial Resistance, 2020
Graphical Abstract.
openaire   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Digital Competence and Literacy: Developing New Narrative Formats. The «Dragon Age: Origins» Videogame [PDF]

, 2011
The approach of this article is centered on the concepts of digital competence and new narrative formats. We aim to apply these dimensions to the videogame «Dragon Age Origins», winner of the 2009 videogame of the year award.
Encabo-Fernández, Eduardo, Jerez-Martínez, Isabel, López-Valero, Amando   +2 more
core   +3 more sources